ArticleBMC evolutionary biology2015
Amino acid transporter expansions associated with the evolution of obligate endosymbiosis in sap-feeding insects (Hemiptera: sternorrhyncha).
Article in BMC evolutionary biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 36 citations in OpenAlex.
- Gut plasma membrane proteomes reflect the distinct feeding strategies of Nezara viridula and Diaphorina citri.Scientific reports · 2026Article
- Functional Analysis of Amino Acid Transporter GenesInsects · 2023Article
- Co-option of a conserved host glutamine transporter facilitates aphid/Proceedings of the National Academy of Sciences of the United States of America · 2023Article
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- Genome-Wide Identification and Characterization of Amino Acid Polyamine Organocation Transporter Family Genes Reveal Their Role in Fecundity Regulation in a Brown Planthopper Species (Frontiers in physiology · 2021Article
- Comparative genomics of Klebsiella michiganensis BD177 and related members of Klebsiella sp. reveal the symbiotic relationship with Bactrocera dorsalis.BMC genetics · 2020Article
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- The Identification and Evolutionary Trends of the Solute Carrier Superfamily in Arthropods.Genome biology and evolution · 2020Article
- Symbiont replacements reset the co-evolutionary relationship between insects and their heritable bacteria.The ISME journal · 2020Article
- Gene Family Evolution in the Pea Aphid Based on Chromosome-Level Genome Assembly.Molecular biology and evolution · 2019Article
- Genome-wide Identification and Expression Analysis of Amino Acid Transporters in the Whitefly,International journal of biological sciences · 2017Article
- Divergent evolution peaks under intermediate population bottlenecks during bacterial experimental evolution.Proceedings. Biological sciences · 2016Article
- Gene Family Expansions in Aphids Maintained by Endosymbiotic and Nonsymbiotic Traits.Genome biology and evolution · 2016Article
- Article
- Annotation of the Asian Citrus Psyllid Genome Reveals a Reduced Innate Immune System.Frontiers in physiology · 2016Article
- Amino acid transporters implicated in endocytosis ofEvoDevo · 2016Article
- Signatures of host/symbiont genome coevolution in insect nutritional endosymbioses.Proceedings of the National Academy of Sciences of the United States of America · 2015Review
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Authors and funding
4 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMutualistic obligate endosymbioses shape the evolution of endosymbiont genomes, but their impact on host genomes remains unclear. Insects of the sub-order Sternorrhyncha (Hemiptera) depend on bacterial endosymbionts for essential amino acids present at low abundances in their phloem-based diet. This obligate dependency has been proposed to explain why multiple amino acid transporter genes are maintained in the genomes of the insect hosts. We implemented phylogenetic comparative methods to test whether amino acid transporters have proliferated in sternorrhynchan genomes at rates grater than expected by chance.
resultsBy applying a series of methods to reconcile gene and species trees, inferring the size of gene families in ancestral lineages, and simulating the null process of birth and death in multi-gene families, we uncovered a 10-fold increase in duplication rate in the AAAP family of amino acid transporters within Sternorrhyncha. This gene family expansion was unmatched in other closely related clades lacking endosymbionts that provide essential amino acids.
conclusionsOur findings support the influence of obligate endosymbioses on host genome evolution by both inferring significant expansions of gene families involved in symbiotic interactions, and discovering increases in the rate of duplication associated with multiple emergences of obligate symbiosis in Sternorrhyncha.
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