Evidence map›Paper›PMID 25887081›Full record

ArticleBMC infectious diseases2015

Seroprevalence of syphilis and human immunodeficiency virus infections among pregnant women who attend the University of Gondar teaching hospital, Northwest Ethiopia: a cross sectional study.

Mengistu Endris, Tekalign Deressa, Yeshambel Belyhun, Feleke Moges

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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  19. Rubella virus,African health sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mengistu EndrisSchool of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O.Box.196, Gondar, Ethiopia. mengistu06@gmail.com.
Tekalign DeressaSchool of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O.Box.196, Gondar, Ethiopia. tekalign09@gmail.com.
Yeshambel BelyhunSchool of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O.Box.196, Gondar, Ethiopia. belyhun@gmail.com.
Feleke MogesSchool of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O.Box.196, Gondar, Ethiopia. Mogesfeleke@gmail.com.
University of Gondar · ETLeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSyphilis and HIV infections in pregnancy result in a number of adverse outcomes including neonatal death and vertical transmission. Ethiopia is a country where these infections are highly prevalent. However, data on co-morbidities of syphilis and HIV among pregnant women in Gondar are scarce. Thus, the aim of this study was to determine the seroprevalence of these infections and associated factors among pregnant women attending antenatal care at the University of Gondar teaching hospital, Northwest Ethiopia.

methodsA cross sectional study was conducted from February to June 2011. Structured interviews were used to collect socio-demographic and obstetric data. Sera against syphilis were screened by rapid plasma reagin test; and confirmed by Treponema pallidum hemagglutination assay. HIV infection was detected by rapid HIV test kits following the national algorithms for HIV testing. Data were summarized by descriptive statistics and binary logistic regression. Odds ratio (OR) and 95% confidence intervals (CI) were calculated.

resultsOf 385 pregnant women, reactive syphilis was noted in 11/385 (2.9%) and seroprevalence of HIV was 43/385 (11.2%). The prevalence of syphilis and HIV co-infection was 2/385(0.5%). High rate of syphilis was observed among the women with above 30 years of age (OR 3.69, 95% CI 0.83 - 16.82). Women with a history of miscarriage and stillbirth were more likely to be infected by syphilis (OR 2.22, 95% CI 0.54-9.60) and (OR 3.24, 95% CI 0.00-17.54), respectively.

conclusionOur data indicated that syphilis and HIV infections are still important public health concerns among pregnant women in the Gondar area. Hence, we recommend strenuous screening of all pregnant women for these infections during antenatal care. Further, strengthening health education on the mode of transmission and prevention of HIV and syphilis is essential for effective control of these infections.

Indexed as

AdultCoinfectionCross-Sectional StudiesEthiopiaFemaleHIV InfectionsHospitals, TeachingHumansInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousPrenatal CarePrevalenceRisk FactorsSeroepidemiologic StudiesSyphilis

Identifiers

PMID25887081
PMCPMC4353477
OpenAlexW2140233714

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.