ArticleBMC genetics2015
Variability of candidate genes, genetic structure and association with sugar accumulation and climacteric behavior in a broad germplasm collection of melon (Cucumis melo L.).
Article in BMC genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 173 citations in OpenAlex.
- Meta genetic analysis of melon sweetness.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Pooled it
- Introgression line libraries in melon (Molecular breeding : new strategies in plant improvement · 2026Review
- CmYAB2 transcriptional module regulates fruit morphogenesis in Cucumis Melo.BMC plant biology · 2026Article
- Unlocking the potential of 'Egusi' melon (Frontiers in plant science · 2025Review
- Genetic Dissection of ToLCNDV Resistance in Resistant Sources ofInternational journal of molecular sciences · 2024Article
- Hybridization Between the Canary Melon and a Vietnamese Non-sweet Melon Cultivar Aiming to Improve the Growth Performance and Fruit Quality in Melon (Cucumis melo L.).Molecular biotechnology · 2024Article
- Time-Series Transcriptome ofGenes · 2024Article
- QTL Mapping and Genome-Wide Association Study Reveal Genetic Loci and Candidate Genes Related to Soluble Solids Content in Melon.Current issues in molecular biology · 2023Article
- New Insights intoInternational journal of molecular sciences · 2022Article
- Pan-genome and multi-parental framework for high-resolution trait dissection in melon (Cucumis melo).The Plant journal : for cell and molecular biology · 2022Article
- Fruit Morphology and Ripening-Related QTLs in a Newly Developed Introgression Line Collection of the Elite Varieties 'Védrantais' and 'Piel de Sapo'.Plants (Basel, Switzerland) · 2022Article
- Advanced Genetic Studies on Powdery Mildew Resistance in TGR-1551.International journal of molecular sciences · 2022Article
- Spanish Melon Landraces: Revealing Useful Diversity by Genomic, Morphological, and Metabolomic Analysis.International journal of molecular sciences · 2022Article
- Mapping of genetic loci controlling fruit linked morphological traits of melon using developed CAPS markers.Molecular biology reports · 2022Article
- Edible Vitalmelon Fruit Extract Inhibits Adipogenesis and Ameliorates High-Fat Diet-Induced Obesity.BioMed research international · 2022Article
- Resistance to Cucumber Green Mottle Mosaic Virus inPlants (Basel, Switzerland) · 2021Article
- QTLs and candidate genes analyses for fruit size under domestication and differentiation in melon (Cucumis melo L.) based on high resolution maps.BMC plant biology · 2021Article
- Resequencing of 297 melon accessions reveals the genomic history of improvement and loci related to fruit traits in melon.Plant biotechnology journal · 2020Article
- Genetic dissection of climacteric fruit ripening in a melon population segregating for ripening behavior.Horticulture research · 2020Article
- Melon Genome Regions Associated with TGR-1551-Derived Resistance toInternational journal of molecular sciences · 2020Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA collection of 175 melon (Cucumis melo L.) accessions (including wild relatives, feral types, landraces, breeding lines and commercial cultivars) from 50 countries was selected to study the phenotypic variability for ripening behavior and sugar accumulation. The variability of single nucleotide polymorphisms (SNPs) at 53 selected candidate genes involved in sugar accumulation and fruit ripening processes was studied, as well as their association with phenotypic variation of related traits.
resultsThe collection showed a strong genetic structure, defining seven groups plus a number of accessions that could not be associated to any of the groups (admixture), which fitted well with the botanical classification of melon varieties. The variability in candidate genes for ethylene, cell wall and sugar-related traits was high and similar to SNPs located in reference genes. Variability at ripening candidate genes had an important weight on the genetic stratification of melon germplasm, indicating that traditional farmers might have selected for ripening traits during cultivar diversification. A strong relationship was also found between the genetic structure and phenotypic diversity, which could hamper genetic association studies. Accessions belonging to the ameri group are the most appropriate for association analysis given the high phenotypic and molecular diversity within the group, and lack of genetic structure. The most remarkable association was found between sugar content and SNPs in LG III, where a hotspot of sugar content QTLs has previously been defined. By studying the differences in allelic variation of SNPs within horticultural groups with specific phenotypic features, we also detected differential variation in sugar-related candidates located in LGIX and LGX, and in ripening-related candidates located in LGII and X, all in regions with previously mapped QTLs for the corresponding traits.
conclusionsIn the current study we have found an important variability at both the phenotypic and candidate gene levels for ripening behavior and sugar accumulation in melon fruit. By combination of differences in allelic diversity and association analysis, we have identified several candidate genes that may be involved in the melon phenotypic diversity.
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