ArticleBMC infectious diseases2015
Prevalence of Mycoplasma genitalium and Mycoplasma hominis in urogenital tract of Brazilian women.
Article in BMC infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05783856 (Application of Vaginal-spraying LiveSpo X-secret in Supporting Treatment of Sexually Transmitted Diseases in Vietnamese Women), which is not on this map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Application of Vaginal-spraying LiveSpo X-secret in Supporting Treatment of Sexually Transmitted Diseases in Vietnamese Women
Who cites it
21 citing papers in PubMed, 50 citations in OpenAlex.
- Trial
- Prevalence ofEpidemiology and infection · 2025Article
- Prevalence ofBiomedical reports · 2023Article
- Burden of Disease of Gonorrhoea in Latin America: Systematic Review and Meta-analysis.Infectious diseases and therapy · 2023Review
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- Development of a RPA-CRISPR-Cas12a Assay for Rapid, Simple, and Sensitive Detection ofFrontiers in microbiology · 2022Article
- Prevalence of Certain Urogenital BacterialThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022Article
- Stroke associated with Mycoplasma hominis infection: a case report.Journal of medical case reports · 2021Article
- Article
- 'Southern African journal of infectious diseases · 2021Article
- Macrolide and fluoroquinolone associated mutations in Mycoplasma genitalium in a retrospective study of male and female patients seeking care at a STI Clinic in Guangzhou, China, 2016-2018.BMC infectious diseases · 2020Article
- Mycoplasma genitalium, a stealth female reproductive tract.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Review
- Mollicutes antibiotic resistance profile and presence of genital abnormalities in couples attending an infertility clinic.The Journal of international medical research · 2020Article
- Male infertility: the intracellular bacterial hypothesis.New microbes and new infections · 2018Review
- Ureaplasma urealyticum and U. parvum in sexually active women attending public health clinics in Brazil.Epidemiology and infection · 2017Article
- Detecting the Diversity ofFrontiers in microbiology · 2017Article
- A Case-control Study on the Relationship betweenOsong public health and research perspectives · 2016Article
- Coinfection of Chlamydiae and other Bacteria in Reactive Arthritis and Spondyloarthritis: Need for Future Research.Microorganisms · 2016Review
- Prevalence of Ureaplasma urealyticum and Mycoplasma hominis in High Vaginal Swab Samples of Infertile Females.Iranian Red Crescent medical journal · 2015Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe role of Mycoplasma hominis and M. genitalium in urogenital tract infections remains unknown. Furthermore these mollicutes present a complex relationship with the host immune response. The role of inflammatory cytokines in infections also makes them good candidates to investigate bacterial vaginosis and mycoplasma genital infections. Therefore, the aim of this study was to detect the above-mentioned mollicutes by quantitative Polymerase Chain Reaction (qPCR) methodologies in vaginal swabs and dosage of cytokines.
methodsVaginal swabs and peripheral blood were collected from 302 women, including healthy individuals. The molecular findings were correlated with some individual behavioral variables, clinical and demographic characteristics, presence of other important microorganisms in vaginal swabs, and levels of interleukin (IL)-1β and IL-6.
resultsM. hominis and M. genitalium were detected in 31.8% and 28.1% of samples, respectively. The qPCR results were associated with clinical signs and symptoms of the infections studied. The frequency of Trichomonas vaginalis, Gardnerella vaginalis, Neisseria gonorrhoeae and Chlamydia trachomatis was 3.0%, 21.5%, 42.4%, and 1.7% respectively. Increased levels of IL-1β were associated with the presence of M. hominis and signs and/or symptoms of the genital infection of women studied.
conclusionIL-1β production was associated with the detection of M. hominis by qPCR. The sexual behavior of women studied was associated with the detection of mycoplasma and other agents of genital infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.