ArticleBMC musculoskeletal disorders2015
The effects of the Korean reference value on the prevalence of osteoporosis and the prediction of fracture risk.
Article in BMC musculoskeletal disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of osteoporosis and incidence of related fractures in developed economies in the Asia Pacific region: a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Pooled it
- Femoral bone mineral density reference values by sex and ethnicity: Findings from the Qatar Biobank study.Osteoporosis and sarcopenia · 2025Article
- Racial and Ethnic Disparities in Bone Health and Outcomes in the United States.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021Review
- Epidemiological investigation of hospitalized patients with traumatic fractures: a cross-sectional study.The Journal of international medical research · 2021Article
- Different reference ranges affect the prevalence of osteoporosis and osteopenia in an urban adult Malaysian population.Osteoporosis and sarcopenia · 2020Article
- Influence of Different Reference Databases on Categorization of Bone Mineral Density: A Study on Rural Postmenopausal Women from Southern India.Indian journal of endocrinology and metabolismArticle
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11 authors.
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Abstract
backgroundSince the reference value is the core factor of the T-score calculation, it has a significant impact on the prevalence of osteoporosis. The purpose of this study was to determine the effects of using the Korean reference value on the prevalence of osteoporosis and on the prediction of fracture risk.
methodsWe used femoral neck bone mineral density (BMD) data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2008-2011. The Korean reference was identified by the mean and standard deviation of men and women aged 20-29 years. We compared the prevalence and the fracture risk assessment tool (FRAX™) probability obtained from the Korean reference and the NHANES III reference.
resultsIn men, the prevalence of osteoporosis increased when using the Korean men's reference, and the difference increased up to 9% for those in their 80s. In women, the prevalence increased when using the NHANES III reference, and the difference increased up to 17% for those in their 80s. The reference value also affected the fracture risk probability, and the difference from changing the reference value increased in women and in subjects with more clinical fracture risk factors. In major osteoporotic fractures, the difference of the risk probability was up to 6% in women aged 70-79 years with two clinical risk factors. For femoral neck fractures, the difference was up to 7% in women aged 50-59 years with two clinical risk factors.
conclusionsWe confirmed that the reference value had significant effects on the prevalence of osteoporosis and on the fracture risk probability. The KNHANES 2008-2011 BMD data reflected the characteristics of the Korean BMD status well with regard to data size and study design; therefore, these data can be used as reference values.
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