Evidence map›Paper›PMID 25886604›Full record

ArticleBMC neurology2015

Chronic inflammatory demyelinating polyneuropathy-like neuropathy as an initial presentation of Crohn's disease.

Suji Kim, Seok-Jae Kang, Ki-Wook Oh, Byung Kyu Ahn, Hang Lak Lee, Dong Soo Han, Kiseok Jang, Young Seo Kim

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Suji KimDepartment of Radiology, Kangbuk Samsung Medical Center, Seoul, Republic of Korea. sjkitty7592@naver.com.
Seok-Jae KangDepartment of Neurology, College of Medicine, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul, 133-792, Republic of Korea. go2dream@hanmail.net.
Ki-Wook OhDepartment of Neurology, College of Medicine, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul, 133-792, Republic of Korea. kiwook.oh@gmail.com.
Byung Kyu AhnDepartment of General Surgery, College of Medicine, Hanyang University, Seoul, Republic of Korea. bkahn@hanyang.ac.kr.
Hang Lak LeeDepartment of Gastroenterology, College of Medicine, Hanyang University, Seoul, Republic of Korea. alwayshang@hanyang.ac.kr.
Dong Soo HanDepartment of Gastroenterology, College of Medicine, Hanyang University, Seoul, Republic of Korea. hands@hanyang.ac.kr.
Kiseok JangDepartment of Pathology, College of Medicine, Hanyang University, Seoul, Republic of Korea. medartisan@hanyang.ac.kr.
Young Seo KimDepartment of Neurology, College of Medicine, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul, 133-792, Republic of Korea. aescula@hanmail.net.
Hanyang University · KRKangbuk Samsung Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic inflammatory demyelinating polyneuropathy (CIDP) is a rare complication of Crohn's disease (CD), and it is uncertain whether it is associated with CD itself or with its treatment. We describe a case of CIDP-like neuropathy as an initial symptom of CD. The neurologic symptoms of the patient which responded partially to intravenous immunoglobulin (IVIG) recovered after resection of the appendiceal CD. CASE PRESENTATION: A 17-year-old male had experienced three separate attacks of motor weakness and paresthesia of all four extremities over a period of 7 months. The electrophysiologic findings revealed a demyelinating sensory-motor polyneuropathy which was compatible with CIDP. However, repeated intravenous IVIG (2 g/kg) treatment gave only a partial response. Four days after the last discharge, he was diagnosed as appendiceal CD after surgical resection of a periappendiceal abscess. His neurologic symptoms and electrophysiologic findings recovered without any maintenance therapy.

conclusionsCIDP-like neuropathy can be an initial presentation of CD, and recovery of the CIDP symptoms may result from resection of the CD. Clinicians should be aware of the possibility of CD in patients with intractable CIDP symptoms.

Indexed as

Abdominal AbscessAdolescentAppendectomyCrohn DiseaseHumansImmunoglobulins, IntravenousImmunologic FactorsMalePolyradiculoneuropathy, Chronic Inflammatory DemyelinatingImmunoglobulins, IntravenousImmunologic Factors

Identifiers

PMID25886604
PMCPMC4379591
OpenAlexW1988010883

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.