ArticleBMC endocrine disorders2015
High prevalence of metabolic syndrome in a mestizo group of adult patients with primary hyperparathyroidism (PHPT).
Article in BMC endocrine disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- Investigating the risk of metabolic and cardiovascular comorbidities among patients with parathyroid cancer: a nationwide representative cohort study in Taiwan.BMC medicine · 2023Article
- Brown Adipose Tissue Biodistribution and Correlations Particularities in Parathyroid Pathology Personalized Diagnosis.Diagnostics (Basel, Switzerland) · 2022Article
- Frequency of Metabolic Syndrome in Paget's Disease of Bone.Sisli Etfal Hastanesi tip bulteni · 2022Article
- Parathyroid gland weight is associated with high density lipoprotein levels in patients with primary hyperparathyroidism.Journal of clinical & translational endocrinology · 2020Article
- Primary hyperparathyroidism and hypertension.Gland surgery · 2020Review
- Additional evidence for the role of parathyroid hormone in adipose tissue browning.EBioMedicine · 2019Article
- The browning of white adipose tissue and body weight loss in primary hyperparathyroidism.EBioMedicine · 2019Article
- Effect of curative parathyroidectomy on insulin resistance.Indian journal of endocrinology and metabolismArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary hyperparathyroidism (PHPT) and metabolic syndrome (MS) have been independently related to cardiovascular morbidities, however this association is still controversial. Mexican population has a high prevalence of metabolic syndrome, however its frequency seems to be even higher than expected in patients with PHPT.
methodsWe retrospectively reviewed the charts of patients that underwent parathyroidectomy for PHPT in a referral center and used the criteria from the National Cholesterol Educational Program (NCEP)/Adult Treatment Panel III (ATP III) to define MS before surgery. We compared the characteristics between the patients with and without MS.
results60 patients were analyzed, 77% were female and 72% had a single parathyroid adenoma. MS was present in 59% of the patients, this group was significantly older (57 vs. 48 years, p = 0.01) and they had lower iPTH (115 vs. 161 ng/ml, p = 0.017). Other parameters did not show differences.
conclusionsMS is frequent in our population diagnosed with primary hyperparathyroidism, adverse cardiovascular parameters are common and significant differences in calcium metabolism compared to the non-MS group are present.
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