Evidence map›Paper›PMID 25886517›Full record

Trial reportBMC cancer2015

Protocol of a multi-centre randomised controlled trial of a web-based information intervention with nurse-delivered telephone support for haematological cancer patients and their support persons.

Jamie Bryant, Rob Sanson-Fisher, William Stevenson, Rochelle Smits, Frans Henskens, Andrew Wei, Flora Tzelepis, Catherine D'Este, Christine Paul, Mariko Carey

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Heterogeneity and associated factors of information needs among patients with hematological malignancies in China: a latent profile analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  3. Do haematological cancer patients get the information they need about their cancer and its treatment? Results of a cross-sectional survey.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Article
  4. Article
  5. Article
  6. Predictors of Post-Traumatic Stress Disorder among Victims of Serious Motor Vehicle Accidents.International journal of community based nursing and midwifery · 2017
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jamie BryantPublic Health/HBRG. HMRI Building, University of Newcastle, Callaghan, NSW, 2308, Australia. Jamie.Bryant@newcastle.edu.au.
Rob Sanson-FisherPublic Health/HBRG. HMRI Building, University of Newcastle, Callaghan, NSW, 2308, Australia. Rob.Sanson-Fisher@newcastle.edu.au.
William StevensonDepartment of Haematology, Royal North Shore Hospital, Kolling Institute of Medical Research, University of Sydney, St Leonards, NSW, 2065, Australia. william.stevenson@sydney.edu.au.
Rochelle SmitsPublic Health/HBRG. HMRI Building, University of Newcastle, Callaghan, NSW, 2308, Australia. Rochelle.Smits@newcastle.edu.au.
Frans HenskensPublic Health/HBRG. HMRI Building, University of Newcastle, Callaghan, NSW, 2308, Australia. Frans.Henskens@newcastle.edu.au.
Andrew WeiThe Australian Centre for Blood Diseases, The Alfred Hospital and Monash University, Melbourne, Australia. A.wei@alfred.org.au.
Flora TzelepisPriority Research Centre for Health Behaviour, University of Newcastle, Callaghan, NSW, 2308, Australia. Flora.Tzelepis@newcastle.edu.au.
Catherine D'EsteNational Centre for Epidemiology and Population Health, Research School of Population Health, The Australian National University, Building 62 Mills Road, Canberra, ACT, 0200, Australia. Catherine.DEste@anu.edu.au.
Christine PaulPublic Health/HBRG. HMRI Building, University of Newcastle, Callaghan, NSW, 2308, Australia. Chris.Paul@newcastle.edu.au.
Mariko CareyPublic Health/HBRG. HMRI Building, University of Newcastle, Callaghan, NSW, 2308, Australia. Mariko.Carey@newcastle.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh rates of anxiety, depression and unmet needs are evident amongst haematological cancer patients undergoing treatment and their Support Persons. Psychosocial distress may be minimised by ensuring that patients are sufficiently involved in decision making, provided with tailored information and adequate preparation for potentially threatening procedures. To date, there are no published studies evaluating interventions designed to reduce psychosocial distress and unmet needs specifically in patients with haematological cancers and their Support Persons. This study will examine whether access to a web-based information tool and nurse-delivered telephone support reduces depression, anxiety and unmet information needs for haematological cancer patients and their Support Persons. METHODS/

designA non-blinded, parallel-group, multi-centre randomised controlled trial will be conducted to compare the effectiveness of a web-based information tool and nurse-delivered telephone support with usual care. Participants will be recruited from the haematology inpatient wards of five hospitals in New South Wales, Australia. Patients diagnosed with acute myeloid leukaemia, acute lymphoblastic leukaemia, Burkitt's lymphoma, Lymphoblastic lymphoma (B or T cell), or Diffuse Large B-Cell lymphoma and their Support Persons will be eligible to participate. Patients and their Support Persons will be randomised as dyads. Participants allocated to the intervention will receive access to a tailored web-based tool that provides accurate, up-to-date and personalised information about: cancer and its causes; treatment options including treatment procedures information; complementary and alternative medicine; and available support. Patients and Support Persons will complete self-report measures of anxiety, depression and unmet needs at 2, 4, 8 and 12 weeks post-recruitment. Patient and Support Person outcomes will be assessed independently. DISCUSSION: This study will assess whether providing information and support using web-based and telephone support address the major psychosocial challenges faced by haematological patients and their Support Persons. The approach, if found to be effective, has potential to improve psychosocial outcomes for haematological and other cancer patients, reduce the complexity and burden of meeting patients' psychosocial needs for health care providers with high potential for translation into clinical practice.

trial registrationACTRN12612000720819.

Indexed as

Social SupportAnxietyAustraliaDepressionFemaleHematologic NeoplasmsHumansInternetMaleNursesQuality of LifeSurveys and QuestionnairesTelephone

Identifiers

PMID25886517
PMCPMC4414364

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.