Evidence map›Paper›PMID 25886289›Full record

ArticleBMC pregnancy and childbirth2015

Validation of thoracic impedance cardiography by echocardiography in healthy late pregnancy.

Jordan P R McIntyre, Kevin M Ellyett, Edwin A Mitchell, Gina M Quill, John Md Thompson, Alistair W Stewart, Robert N Doughty, Peter R Stone, Maternal Sleep in Pregnancy Study Group

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04330742 (The Influence of Intravascular Fluid Administration on Aortic Velocity Time Integral in Obstetric Patients Undergoing Cesarean Section), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04330742 unknown statusnot on this mapstarted 2020, after this paper: background citation

The Influence of Intravascular Fluid Administration on Aortic Velocity Time Integral in Obstetric Patients Undergoing Cesarean Section

TypeobservationalSponsorBaylor College of MedicineRan2020 to 2025Enrolled50ConditionsPregnancy Related, Hemorrhage, Fluid Overload, Labor ComplicationArmslactated ringers
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  3. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jordan P R McIntyreDepartment of Obstetrics and Gynaecology, Faculty of Medical and Health Sciences, University of Auckland, Level 12, Support Building, Auckland City Hospital, Private Bag 92019, Auckland, New Zealand. j.mcintyre@auckland.ac.nz.
Kevin M EllyettRespiratory Measurement Laboratory, Auckland District Health Board, Auckland, New Zealand. KEllyett@adhb.govt.nz.
Edwin A MitchellDepartment of Paediatrics, University of Auckland, Auckland, New Zealand. e.mitchell@auckland.ac.nz.
Gina M QuillDepartment of Medicine, University of Auckland, Auckland, New Zealand. g.quill@auckland.ac.nz.
John Md ThompsonDepartment of Paediatrics, University of Auckland, Auckland, New Zealand. j.thompson@auckland.ac.nz.
Alistair W StewartDepartment of Epidemiology and Biostatistics, School of Population Health, University of Auckland, Auckland, New Zealand. aw.stewart@auckland.ac.nz.
Robert N DoughtyDepartment of Medicine, University of Auckland, Auckland, New Zealand. r.doughty@auckland.ac.nz.
Peter R StoneDepartment of Obstetrics and Gynaecology, Faculty of Medical and Health Sciences, University of Auckland, Level 12, Support Building, Auckland City Hospital, Private Bag 92019, Auckland, New Zealand. p.stone@auckland.ac.nz.
Maternal Sleep in Pregnancy Study Group
University of Auckland · NZAuckland City Hospital · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAssessment of stroke volume (SV) is often necessary in clinical and research settings. The clinically established method for SV assessment in pregnancy is echocardiography, but given its limitations, it is not always an appropriate measurement tool. Thoracic impedance cardiography (ICG) allows continuous, non-invasive SV assessment. However, SV determination relies on assumptions regarding the thoracic shape that may mean the algorithm is not valid in pregnancy. The available data regarding the validity of ICG against an established reference standard using modern SV algorithms are both limited and conflicting. We aimed to test the validity of ICG in a clinically realistic setting in late pregnancy using echocardiography.

methodsTwenty-nine women in late pregnancy underwent standard echocardiography assessments with simultaneous ICG measurement. Agreement between devices was tested using Bland-Altman analysis.

resultsBland-Altman analysis of the relationship between ICG and echocardiography demonstrated that the 95% limits of agreement exceeded acceptable or expected ranges. Measures of maternal and fetal anthropometry do not account for the lack of agreement.

conclusionsAbsolute values of SV as determined by ICG are not valid in pregnancy. Further work is required to examine the ability of ICG to assess relative changes in maternal haemodynamics in late pregnancy.

Indexed as

Cardiography, ImpedanceEchocardiographyHemodynamicsAdultComparative Effectiveness ResearchFemaleHumansPregnancyPregnancy Trimester, ThirdReference StandardsReproducibility of ResultsStroke Volume

Identifiers

PMID25886289
PMCPMC4389339
OpenAlexW1967557284

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.