Evidence map›Paper›PMID 25886265›Full record

Trial reportBMC psychiatry2015

A randomised controlled trial of positive memory training for the treatment of depression within schizophrenia.

Craig Steel, Mark van der Gaag, Kees Korrelboom, Judit Simon, Peter Phiri, M Fazil Baksh, Til Wykes, Diana Rose, Suzanna Rose, Mark Hardcastle and 3 more

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Cost-Effectiveness of Positive Memory Training (PoMeT) for the Treatment of Depression in Schizophrenia.International journal of environmental research and public health · 2022
    Trial
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  15. Measuring broader wellbeing in mental health services: validity of the German language OxCAP-MH capability instrument.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 3 countries.

Craig SteelSchool of Psychology and Clinical Language Sciences, University of Reading, Reading, RG6 6AL, UK. c.steel@reading.ac.uk.
Mark van der GaagVU University and EMGO Institute for Health and Care Research, van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands. m.vander.gaag@vu.nl.
Kees KorrelboomPsyQ, Parnassia-Bavo Psychiatric Centre, Stadhoudersplantsoen 2, 2517 JL, The Hague, The Netherlands. k.korrelboom@psyq.nl.
Judit SimonDepartment of Health Economics, Centre for Public Health, Medical University of Vienna, Vienna, Austria. judit.simon@meduniwien.ac.at.
Peter PhiriSouthern Health NHS Foundation Trust, Southampton, SO30 3JB, UK. peter.phiri@southernhealth.nhs.uk.
M Fazil BakshSchool of Mathematical and Physical Sciences, University of Reading, Reading, RG6 6AL, UK. m.f.baksh@reading.ac.uk.
Til WykesDepartment of Psychology, Institute of Psychiatry, King's College London, De Crespigny Park, London, SE5 8AF, UK. Til.Wykes@kcl.ac.uk.
Diana RoseHealth Service Research Department, Institute of Psychiatry, King's College London, De Crespigny Park, London, SE5 8AF, UK. Diana.Rose@kcl.ac.uk.
Suzanna RoseBerkshire Healthcare Foundation Trust, Bracknell, RG12 ILH, UK. Suzanna.Rose@berkshire.nhs.uk.
Mark HardcastleBerkshire Healthcare Foundation Trust, Bracknell, RG12 ILH, UK. Mark.Hardcastle@berkshire.nhs.uk.
Simon EnrightBerkshire Healthcare Foundation Trust, Bracknell, RG12 ILH, UK. Simon.Enright@berkshire.nhs.uk.
Gareth EvansBerkshire Healthcare Foundation Trust, Bracknell, RG12 ILH, UK. Gareth.Evans@berkshire.nhs.uk.
David KingdonDepartment of Medicine, University of Southampton, Southampton, SO17 1BJ, UK. D.Kingdon@soton.ac.uk.
Berkshire Healthcare NHS Foundation Trust · GBKing's College London · GBUniversity of Reading · GBEMGO Institute for Health and Care Research · NLMedical University of Vienna · ATParnassia Groep · NLSouthern Health NHS Foundation Trust · GBUniversity of Southampton · GB

Funding

Department of Health PB-PG-0712-28021
6 · The paper itself

Abstract

backgroundDepression is highly prevalent within individuals diagnosed with schizophrenia, and is associated with an increased risk of suicide. There are no current evidence based treatments for low mood within this group. The specific targeting of co-morbid conditions within complex mental health problems lends itself to the development of short-term structured interventions which are relatively easy to disseminate within health services. A brief cognitive intervention based on a competitive memory theory of depression, is being evaluated in terms of its effectiveness in reducing depression within this group. METHODS/

designThis is a single blind, intention-to-treat, multi-site, randomized controlled trial comparing Positive Memory Training plus Treatment as Usual with Treatment as Usual alone. Participants will be recruited from two NHS Trusts in Southern England. In order to be eligible, participants must have a DSM-V diagnosis of schizophrenia or schizo-affective disorder and exhibit at least a mild level of depression. Following baseline assessment eligible participants will be randomly allocated to either the Positive Memory Training plus Treatment as Usual group or the Treatment as Usual group. Outcome will be assessed at the end of treatment (3-months) and at 6-month and 9-month post randomization by assessors blind to group allocation. The primary outcome will be levels of depression and secondary outcomes will be severity of psychotic symptoms and cost-effectiveness. Semi-structured interviews will be conducted with all participants who are allocated to the treatment group so as to explore the acceptability of the intervention. DISCUSSION: Cognitive behaviour therapy is recommended for individuals diagnosed with schizophrenia. However, the number of sessions and length of training required to deliver this intervention has caused a limit in availability. The current trial will evaluate a short-term structured protocol which targets a co-morbid condition often considered of primary importance by service users. If successful the intervention will be an important addition to current initiatives aimed at increasing access to psychological therapies for people diagnosed with severe mental health problems.

trial registrationCurrent Controlled Trials. ISRCTN99485756 . Registered 13 March 2014.

Indexed as

Cognitive Behavioral TherapyMemoryResearch DesignAdolescentAdultAgedDepressive DisorderEnglandFemaleHumansMaleMiddle AgedSchizophreniaSingle-Blind MethodYoung Adult

Identifiers

PMID25886265
PMCPMC4414283
OpenAlexW2108546024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.