Evidence map›Paper›PMID 25886096›Full record

ReviewAnesthesia, essays and researches

Improved prophylaxis of postoperative nausea vomiting: Palonosetron a novel antiemetic.

Akshaya N Shetti, Dewan Roshan Singh, Kusha Nag, Rachita A Shetti, V R Hemanth Kumar

Open access · greenAbstract readReview
In one paragraph

Review in Anesthesia, essays and researches. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Akshaya N ShettiDepartment of Anaesthesiology and Critical Care, Krishna Institute of Medical Sciences, Karad, Maharashtra, India.
Dewan Roshan SinghDepartment of Anaesthesiology, Mahatma Gandhi Medical College and Research Institute, Pondicherry, India.
Kusha NagDepartment of Anaesthesiology, Mahatma Gandhi Medical College and Research Institute, Pondicherry, India.
Rachita A ShettiDepartment of Paedodontics and Preventive Dentistry, School of Dental Sciences, Karad, Maharashtra, India.
V R Hemanth KumarDepartment of Anaesthesiology, Mahatma Gandhi Medical College and Research Institute, Pondicherry, India.
Mahatma Gandhi Medical College and Research Institute · INKrishna Institute of Medical Sciences Deemed University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many anti-emetics are used in clinical practice. Palonosetron hydrochloride is one of them. It is a novel, centrally acting antiemetic, and anti-nausea agent. This drug is an antagonist of serotonin receptor subtype 3 (5-HT3). This drug has longer duration of action which makes it useful in the prevention and treatment of acute and delayed onset of nausea and vomiting. This drug was initially used for chemotherapy induced nausea and vomiting. Federal drug agency (FDA) has approved it for prevention and treatment of post-operative nausea and vomiting. The literature search for this article was done using Google scholar and Pubmed using the terms "Palonosetron," "longer duration of action," "nausea," "vomiting," and "postoperative".

Indexed as

5-HT3anesthesiaAntiemeticsnauseapalonosetronpost-operativevomiting

Identifiers

PMID25886096
PMCPMC4173575
OpenAlexW2034044769

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.