ArticleBMC cancer2015
Epidemiological patterns of asbestos exposure and spatial clusters of incident cases of malignant mesothelioma from the Italian national registry.
Article in BMC cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 62 citations in OpenAlex.
- Detailed mapping of mesothelioma cases in Denmark to identify areas with elevated risk: a nationwide population-based study.Scandinavian journal of work, environment & health · 2025Article
- Sex differences in asbestos exposure.Frontiers in public health · 2025Review
- Caregivers of patients with malignant pleural mesothelioma: who provides care, what care do they provide and what burden do they experience?Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Current causes of mesothelioma: how has the asbestos ban changed the perspective?Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2023Review
- The Italian Experience in the Development of Mesothelioma Registries: A Pathway for Other Countries to Address the Negative Legacy of Asbestos.International journal of environmental research and public health · 2023Article
- An Approach to Overcome the Limitations of Surveillance of Asbestos Related Diseases in Low- and Middle-Income Countries: What We Learned from the Sibaté Study in Colombia.Annals of global health · 2023Article
- Recommendations for Implementing Lung Cancer Screening with Low-Dose Computed Tomography in Europe.Cancers · 2020Review
- Analyzing biological and molecular characteristics and genomic damage induced by exposure to asbestos.Cancer management and research · 2019Review
- Article
- Hotspots of malignant pleural mesothelioma in Western Europe.Translational lung cancer research · 2018Review
- Asbestos Exposure and the Mesothelioma Incidence in Poland.International journal of environmental research and public health · 2018Article
- Temporal Patterns of Exposure to Asbestos and Risk of Asbestosis: An Analysis of a Cohort of Asbestos Textile Workers.Journal of occupational and environmental medicine · 2018Article
- Soluble CD157 in pleural effusions: a complementary tool for the diagnosis of malignant mesothelioma.Oncotarget · 2018Article
- "The Less I Think About It, the Better I Feel": A Thematic Analysis of the Subjective Experience of Malignant Mesothelioma Patients and Their Caregivers.Frontiers in psychology · 2018Article
- Epidemiology of malignant mesothelioma in Italy: surveillance systems, territorial clusters and occupations involved.Journal of thoracic disease · 2018Article
- Asbestos Ban in Italy: A Major Milestone, Not the Final Cut.International journal of environmental research and public health · 2017Article
- Turkey National Mesothelioma Surveillance and Environmental Asbestos Exposure Control Program.International journal of environmental research and public health · 2017Article
- Environmental asbestos exposure and risk of mesothelioma.Annals of translational medicine · 2017Review
- Recent Scientific Evidence Regarding Asbestos Use and Health Consequences of Asbestos Exposure.Current environmental health reports · 2016Review
- Occupational exposure in the removal and disposal of asbestos-containing materials in Italy.International archives of occupational and environmental health · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors at 20 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious ecological spatial studies of malignant mesothelioma cases, mostly based on mortality data, lack reliable data on individual exposure to asbestos, thus failing to assess the contribution of different occupational and environmental sources in the determination of risk excess in specific areas. This study aims to identify territorial clusters of malignant mesothelioma through a Bayesian spatial analysis and to characterize them by the integrated use of asbestos exposure information retrieved from the Italian national mesothelioma registry (ReNaM).
methodsIn the period 1993 to 2008, 15,322 incident cases of all-site malignant mesothelioma were recorded and 11,852 occupational, residential and familial histories were obtained by individual interviews. Observed cases were assigned to the municipality of residence at the time of diagnosis and compared to those expected based on the age-specific rates of the respective geographical area. A spatial cluster analysis was performed for each area applying a Bayesian hierarchical model. Information about modalities and economic sectors of asbestos exposure was analyzed for each cluster.
resultsThirty-two clusters of malignant mesothelioma were identified and characterized using the exposure data. Asbestos cement manufacturing industries and shipbuilding and repair facilities represented the main sources of asbestos exposure, but a major contribution to asbestos exposure was also provided by sectors with no direct use of asbestos, such as non-asbestos textile industries, metal engineering and construction. A high proportion of cases with environmental exposure was found in clusters where asbestos cement plants were located or a natural source of asbestos (or asbestos-like) fibers was identifiable. Differences in type and sources of exposure can also explain the varying percentage of cases occurring in women among clusters.
conclusionsOur study demonstrates shared exposure patterns in territorial clusters of malignant mesothelioma due to single or multiple industrial sources, with major implications for public health policies, health surveillance, compensation procedures and site remediation programs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.