Evidence map›Paper›PMID 25885891›Full record

ArticleBMC neurology2015

Pure sensory chronic inflammatory polyneuropathy: rapid deterioration after steroid treatment.

Elisabeth Chroni, Dimitra Veltsista, Evangelia Gavanozi, Tavitha Vlachou, Panagiotis Polychronopoulos, Panagiotis Papathanasopoulos

Abstract readCase Reports
In one paragraph

Article in BMC neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Treatment Approaches for Atypical CIDP.Frontiers in neurology · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elisabeth ChroniDepartment of Neurology, School of Medicine, University of Patras, Patras, Greece. echroni@yahoo.com.
Dimitra VeltsistaDepartment of Neurology, School of Medicine, University of Patras, Patras, Greece. dveltsista@yahoo.gr.
Evangelia GavanoziDepartment of Neurology, School of Medicine, University of Patras, Patras, Greece. evigavanozi@yahoo.gr.
Tavitha VlachouDepartment of Neurology, School of Medicine, University of Patras, Patras, Greece. tavivlachou@yahoo.gr.
Panagiotis PolychronopoulosDepartment of Neurology, School of Medicine, University of Patras, Patras, Greece. ppolychr@yahoo.gr.
Panagiotis PapathanasopoulosDepartment of Neurology, School of Medicine, University of Patras, Patras, Greece. papat@upatras.gr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic inflammatory demyelinating polyneuropathy (CIDP) as a pure sensory variant is rarely encountered. Therefore the best treatment option is hard to define. CASE PRESENTATIONS: We reported two middle-aged patients of Caucasian origin, one female and one male, who over a period of several months presented limbs and gait ataxia. Clinical and neurophysiological examination revealed only sensory abnormalities. A diagnosis of atypical CIDP was suggested, considering the elevated CSF protein level and the presence of anti-gangliosides antibodies. Ten and 15 days respectively after initiation of prednisolone treatment both patients experienced exacerbation of sensory symptoms and emerging of muscle weakness. Steroids were then substituted by rituximab in the first patient and intravenous immunoglobulin in the second patient resulting in gradual decrement of symptoms and signs. Two-year follow-up showed no further deterioration.

conclusionCaution should be exercised when treating cases of pure sensory polyneuropathy with high dose steroids since an unfavorable outcome is possible.

Indexed as

Disease ProgressionFemaleGlucocorticoidsHumansImmunoglobulins, IntravenousImmunologic FactorsMaleMiddle AgedMuscle WeaknessNeural ConductionPolyradiculoneuropathy, Chronic Inflammatory DemyelinatingPrednisoloneRituximabGlucocorticoidsImmunoglobulins, IntravenousImmunologic FactorsPrednisoloneRituximab

Identifiers

PMID25885891
PMCPMC4359520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.