SynthesisBMC medical ethics2015
A systematic review of empirical bioethics methodologies.
Synthesis in BMC medical ethics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Preferences, attitudes and views regarding genetic newborn screening (gNBS) for rare diseases: a systematic review of the literature and synthesis from 2009 to 2022.Orphanet journal of rare diseases · 2026Pooled it
- Bioethics at the intersection of politics, society, and healthcare: the significance of media debate analyses.BMC medical ethics · 2025Pooled it
- Non-empirical methods for ethics research on digital technologies in medicine, health care and public health: a systematic journal review.Medicine, health care, and philosophy · 2024Pooled it
- Ethical issues in genomics research in persons with Alzheimer's Disease/Alzheimer's Disease-related dementia (AD/ADRD): a systematic review.BMC medical ethics · 2024Pooled it
- Bioethical knowledge in students and health professionals: a systematic review.Frontiers in medicine · 2024Pooled it
- What methods do reviews of normative ethics literature use for search, selection, analysis, and synthesis? In-depth results from a systematic review of reviews.Systematic reviews · 2017Pooled it
- Pooled it
- To what extent should doctors communicate diagnostic uncertainty with their patients? An empirical ethics vignette study.Journal of medical ethics · 2025Trial
- Empirical Bioethics-Historical, Philosophical, and Methodological Perspectives.Journal of bioethical inquiry · 2026Article
- Digital bioethics: exploring an emerging field.Medicine, health care, and philosophy · 2026Article
- Guiding the Ethics of Locator Devices in Dementia Care: Tutorial on Developing a Question-Based Ethical Framework.Journal of medical Internet research · 2026Article
- Bioethics-in-Science : An Invitation.Journal of bioethical inquiry · 2026Article
- Strengthening an Ethical Framework and Research Practice to Better Link Global Health Research to Health Equity : A Case Study of the SPOT-Impact Consortium.Journal of bioethical inquiry · 2026Article
- Ethical Expertise Before and After Medically Assisted Dying: The Informal and Formal Role of the Ethicist in the Netherlands.Bioethics · 2026Article
- Childhood vaccine refusal in Türkiye: a dual perspective qualitative study of parents and healthcare workers.Frontiers in public health · 2026Article
- Integrating ethics in digital mental healthcare technologies: a principle-based empirically grounded roadmap approach.Medicine, health care, and philosophy · 2025Article
- History, Hype, and Responsible Psychedelic Medicine: A Qualitative Study of Psychedelic Researchers.Journal of bioethical inquiry · 2025Article
- Dual-roles and beyond: values, ethics, and practices in forensic mental health decision-making.Medicine, health care, and philosophy · 2025Article
- The ethical canary: narrow reflective equilibrium as a source of moral justification in healthcare priority-setting.Journal of medical ethics · 2024Article
- What does "urgency" mean when prioritizing cancer treatment? Results from a qualitative study with German oncologists and other experts during the COVID-19 pandemic.Journal of cancer research and clinical oncology · 2024Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite the increased prevalence of bioethics research that seeks to use empirical data to answer normative research questions, there is no consensus as to what an appropriate methodology for this would be. This review aims to search the literature, present and critically discuss published Empirical Bioethics methodologies.
methodsMedLine, Web of Science and Google Scholar were searched between 15/02/12 and 16/06/13 to find relevant papers. These were abstract reviewed independently by two reviewers with papers meeting the inclusion criteria subjected to data extraction.
results33 publications (32 papers and one book chapter) were included which contained 32 distinct methodologies. The majority of these methodologies (n = 22) can be classed as either dialogical or consultative, and these represent two extreme 'poles' of methodological orientation. Consideration of these results provoked three central questions that are central to the planning of an empirical bioethics study, and revolve around how a normative conclusion can be justified, the analytic process through which that conclusion is reached, and the kind of conclusion that is sought.
conclusionWhen considering which methodology or research methods to adopt in any particular study, researchers need to think carefully about the nature of the claims they wish to generate through their analyses, and how these claims align with the aims of the research. Whilst there are superficial similarities in the ways that identical research methods are made use of, the different meta-ethical and epistemological commitments that undergird the range of methodological approaches adopted rehearse many of the central foundational disagreements that play out within moral philosophy and bioethical analysis more broadly. There is little common ground that transcends these disagreements, and we argue that this is likely to present a challenge for the legitimacy of the bioethical enterprise. We conclude, however, that this heterogeneity ought to be welcomed, but urge those involved in the field to engage meaningfully and explicitly with questions concerning what kinds of moral claim they want to be able to make, about normative justification and the methodological process, and about the coherence of these components within their work.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.