Evidence map›Paper›PMID 25885440›Full record

ArticleBMC ophthalmology2015

Bilateral cystoid macular edema following docetaxel chemotherapy in a patient with retinitis pigmentosa: a case report.

Anna Enzsoly, Kinga Kammerer, Janos Nemeth, Miklos Schneider

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  7. Docetaxel Retinopathy: A Case Report.Case reports in ophthalmology
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Anna EnzsolyDepartment of Ophthalmology, Semmelweis University, Faculty of Medicine, H-1085 Maria u. 39, Budapest, Hungary. enzsoly.anna@med.semmelweis-univ.hu.
Kinga KammererDepartment of Oncology, Flor Ferenc Hospital of Pest County, Kistarcsa, Hungary. kkammerer@florhosp.hu.
Janos NemethDepartment of Ophthalmology, Semmelweis University, Faculty of Medicine, H-1085 Maria u. 39, Budapest, Hungary. nemeth.janos@med.semmelweis-univ.hu.
Miklos SchneiderDepartment of Ophthalmology, Semmelweis University, Faculty of Medicine, H-1085 Maria u. 39, Budapest, Hungary. schneider.miklos@med.semmelweis-univ.hu.
Semmelweis University · HUJahn Ferenc Dél-Pesti Kórház és Rendelőintézet · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDocetaxel is a chemotherapeutic agent of the taxane class of drugs for the treatment of breast cancer. We present a female patient who noted decreased vision after docetaxel treatment. CASE PRESENTATION: A 45-year-old female patient received docetaxel treatment after resection of a breast carcinoma. Funduscopy and optical coherence tomography (OCT) showed cystoid macular edema on both eyes. Dilated funduscopy also showed bone spicule-like pigmented deposits, typical for retinitis pigmentosa. Besides the fundus appearance restricted peripheral vision and scotopic electroretinogram confirmed the diagnosis of retinitis pigmentosa. Chemotherapy was discontinued following a consulation with the oncologist of the patient. After five weeks, visual acuity improved significantly along with decrease of retinal thickness measured by OCT.

conclusionDocetaxel may cause ocular adverse effects such as cystoid macular edema. Ophthalmological examination is warranted for patients with visual complaints during docetaxel chemotherapy.

Indexed as

Antineoplastic AgentsBreast NeoplasmsDocetaxelDose-Response Relationship, DrugElectroretinographyFemaleFluorescein AngiographyFundus OculiHumansMacular EdemaMiddle AgedRetinitis PigmentosaTaxoidsTomography, Optical CoherenceVisual AcuityAntineoplastic AgentsDocetaxelTaxoids

Identifiers

PMID25885440
PMCPMC4392864
OpenAlexW2060623561

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.