Evidence map›Paper›PMID 25885225›Full record

Observational studyBMC psychiatry2015

Validation of life-charts documented with the personal life-chart app - a self-monitoring tool for bipolar disorder.

Lars O Schärer, Ute J Krienke, Sandra-Mareike Graf, Katharina Meltzer, Jens M Langosch

Abstract readMulticenter StudyObservational StudyValidation Study
In one paragraph

Observational study in BMC psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Differential impact of manic versus depressive episode recurrence on longitudinal gray matter volume changes in bipolar disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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  17. Big data for bipolar disorder.International journal of bipolar disorders · 2016
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lars O SchärerDepartment of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany. lars.schaerer@uniklinik-freiburg.de.
Ute J KrienkeBethanien Hospital for Psychiatry, Psychosomatics and Psychotherapy, Gützkower Landstrasse 69, Greifswald, 17489, Germany. krienke@odebrecht-stiftung.de.
Sandra-Mareike GrafDepartment of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany. sandra-mareike.graf@uniklinik-freibung.de.
Katharina MeltzerDepartment of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany. kathimeltzer@hotmail.com.
Jens M LangoschDepartment of Psychiatry and Psychotherapy, University of Freiburg Medical Center, Freiburg, Germany. langosch@odebrecht-stiftung.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong-term monitoring in bipolar affective disorders constitutes an important therapeutic and preventive method. The present study examines the validity of the Personal Life-Chart App (PLC App), in both German and in English. This App is based on the National Institute of Mental Health's Life-Chart Method, the de facto standard for long-term monitoring in the treatment of bipolar disorders.

methodsMethods have largely been replicated from 2 previous Life-Chart studies. The participants documented Life-Charts with the PLC App on a daily basis. Clinicians assessed manic and depressive symptoms in clinical interviews using the Inventory of Depressive Symptomatology, clinician-rated (IDS-C) and the Young Mania Rating Scale (YMRS) on a monthly basis on average. Spearman correlations of the total scores of IDS-C and YMRS were calculated with both the Life-Chart functional impairment rating and mood rating documented with the PLC App. 44 subjects used the PLC App in German and 10 subjects used the PLC App in English. 118 clinical interviews from the German sub-sample and 97 from the English sub-sample were analysed separately.

resultsThe results in both sub-samples are similar to previous Life-Chart validation studies. Again statistically significant high correlations were found between the Life-Chart function rating assigned through the PLC App and well-established observer-rated methods. Again correlations were weaker for the Life-Chart mood rating than for the Life-Chart function impairment. No relevant correlation was found between the Life-chart mood rating and YMRS in the German sub-sample.

conclusionThis study gives further evidence for the validity of the Life-Chart method as a valid tool for the recognition of both manic and depressive episodes. Documenting Life-Charts with the PLC App (English and German) does not seem to impair the validity of patient ratings.

Indexed as

AdultBipolar DisorderDepressionFemaleHumansLanguageMaleProspective StudiesPsychiatric Status Rating ScalesQuality of LifeSelf CareTranslating

Identifiers

PMID25885225
PMCPMC4367878

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.