Evidence map›Paper›PMID 25885168›Full record

SynthesisBMC cancer2015

Effects of supervised exercise on cancer-related fatigue in breast cancer survivors: a systematic review and meta-analysis.

José Francisco Meneses-Echávez, Emilio González-Jiménez, Robinson Ramírez-Vélez

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 29 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed, 29 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 29 syntheses or guidelines pooled it, 353 citations in OpenAlex.

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  5. Impact of resistance training on fatigue among breast cancer patients undergoing chemotherapy: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  9. Effect of exercise interventions in adults with cancer receiving palliative care: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  10. Effectiveness of exercise interventions in the management of cancer-related fatigue: a systematic review of systematic reviews.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  19. Systematic review and meta-analysis of maintenance of physical activity behaviour change in cancer survivors.The international journal of behavioral nutrition and physical activity · 2019
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79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

José Francisco Meneses-EchávezGrupo GICAEDS. Facultad de Cultura Física, Deporte y Recreación, Universidad Santo Tomás, Bogotá, D.C, Colombia. menesesjose77@gmail.com.
Emilio González-JiménezDepartamento de Enfermería. Facultad de Ciencias de la Salud, Universidad de Granada, Granada, Spain. emigoji@ugr.es.
Robinson Ramírez-VélezGrupo GICAEDS. Facultad de Cultura Física, Deporte y Recreación, Universidad Santo Tomás, Bogotá, D.C, Colombia. robin640@hotmail.com.
Universidad Santo Tomás · COUniversidad de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer-related fatigue (CRF) is the most common and distressing symptom in breast cancer survivors. Approximately 40% to 80% of cancer patients undergoing active treatment suffer from CRF. Exercise improves overall quality of life and CRF; however, the specific effects of the training modalities are not well understood.

methodsThis study aimed to determine the pooled effects of supervised exercise interventions on CRF in breast cancer survivors. We searched PubMed/MEDLINE, EMBASE, Scopus, CENTRAL and CINAHL databases between December 2013 and January 2014 without language restrictions. Risk of bias and methodological quality were evaluated using the PEDro score. Pooled effects were calculated with a random-effects model according to the DerSimonian and Laird method. Heterogeneity was evaluated with the I (2) test.

resultsNine high-quality studies (n = 1156) were finally included. Supervised aerobic exercise was statistically more effective than conventional care in improving CRF among breast cancer survivors (SMD = -0.51, 95%CI -0.81 to -0.21), with high statistical heterogeneity (P = 0.001; I (2)  = 75%). Similar effects were found for resistance training on CRF (SMD = -0.41, 95%CI -0.76 to -0.05; P = 0.02; I(2) = 64%). Meta-regression analysis revealed that exercise volume parameters are closely related with the effect estimates on CRF. Egger's test suggested moderate evidence of publication bias (P = 0.04).

conclusionsSupervised exercise reduces CRF and must be implemented in breast cancer rehabilitation settings. High-volume exercises are safe and effective in improving CRF and overall quality of life in women with breast cancer. Further research is encouraged.

trial registrationCRD42014007223.

Indexed as

Breast NeoplasmsExercise TherapyFatigueFemaleHumansQuality of LifeSurvivors

Identifiers

PMID25885168
PMCPMC4364505
OpenAlexW2039342400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.