Trial reportJournal of neuroengineering and rehabilitation2015
Adaptive training with full-body movements to reduce bradykinesia in persons with Parkinson's disease: a pilot study.
Trial report in Journal of neuroengineering and rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Recent advances in rehabilitation for Parkinson's Disease with Exergames: A Systematic Review.Journal of neuroengineering and rehabilitation · 2019Pooled it
- Markerless motion capture systems as training device in neurological rehabilitation: a systematic review of their use, application, target population and efficacy.Journal of neuroengineering and rehabilitation · 2017Pooled it
- A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.Sensors (Basel, Switzerland) · 2016Pooled it
- The feasibility and positive effects of a customised videogame rehabilitation programme for freezing of gait and falls in Parkinson's disease patients: a pilot study.Journal of neuroengineering and rehabilitation · 2018Trial
- Article
- Article
- Effect of Structured Exercise for the Rehabilitation of Patients With Chronic Parkinson's Disease.Cureus · 2026Article
- Gamification Integration in Technological Devices for Motor Rehabilitation in Parkinson Disease: Scoping Review.JMIR serious games · 2025Review
- Machine learning for early detection and severity classification in people with Parkinson's disease.Scientific reports · 2025Article
- Article
- Analysis of Movement Entropy during Community Dance Programs for People with Parkinson's Disease and Older Adults: A Cohort Study.International journal of environmental research and public health · 2022Article
- Spatio-temporal parameters of ataxia gait dataset obtained with the Kinect.Data in brief · 2020Article
- Exploring Movement Impairments in Patients With Parkinson's Disease Using the Microsoft Kinect Sensor: A Feasibility Study.Frontiers in neurology · 2020Article
- Article
- Using a Somatosensory Controller to Assess Body Size for Size-Specific Dose Estimates in Computed Tomography.BioMed research international · 2018Article
- Effect of Position- and Velocity-Dependent Forces on Reaching Movements at Different Speeds.Frontiers in human neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBradykinesia (slow movements) is a common symptom of Parkinson's disease (PD) and results in reduced mobility and postural instability. The objective of this study is to develop and demonstrate a technology-assisted exercise protocol that is specifically aimed at reducing bradykinesia.
methodsSeven persons with PD participated in this study. They were required to perform whole body reaching movements toward targets placed in different directions and at different elevations. Movements were recorded by a Microsoft Kinect movement sensor and used to control a human-like avatar, which was continuously displayed on a screen placed in front of the subjects. After completion of each movement, subjects received a 0-100 score that was inversely proportional to movement time. Target distance in the next movements was automatically adjusted in order to keep the score around a pre-specified target value. In this way, subjects always exercised with the largest movement amplitude they could sustain. The training protocol was organised into blocks of 45 movements toward targets placed in three different directions and at three different elevations (a total of nine targets). Each training session included a finite number of blocks, fitted within a fixed 40 minutes duration. The whole protocol included a total of 10 sessions (approximately two sessions/week). As primary outcome measure we took the absolute average acceleration. Various aspects of movement performance were taken as secondary outcome measures, namely accuracy (undershoot error), path curvature, movement time, and average speed.
resultsThroughout sessions, we observed an increase of the absolute average acceleration and speed and decreased undershoot error and movement time. Exercise also significantly affected the relationship between target elevation and both speed and acceleration - the improvement was greater at higher elevations.
conclusionsThe device and the protocol were well accepted by subjects and appeared safe and easy to use. Our preliminary results point at a training-induced reduction of bradykinesia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.