Evidence map›Paper›PMID 25885092›Full record

Observational studyPloS one2015

Testing initiatives increase rates of HIV diagnosis in primary care and community settings: an observational single-centre cohort study.

Prini Mahendran, Suneeta Soni, Stephanie Goubet, Emma Saunsbury, Jonathan Roberts, Martin Fisher

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Prini MahendranDepartment of GU Medicine, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom.
Suneeta SoniDepartment of GU Medicine, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom.
Stephanie GoubetClinical Investigations and Research Unit, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom.
Emma SaunsburyBrighton and Sussex Medical School, Brighton, United Kingdom.
Jonathan RobertsDepartment of GU Medicine, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom.
Martin FisherDepartment of GU Medicine, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom; Brighton and Sussex Medical School, Brighton, United Kingdom.
University Hospitals Sussex NHS Foundation Trust · GBBrighton and Sussex Medical School · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe primary objective was to examine trends in new HIV diagnoses in a UK area of high HIV prevalence between 2000 and 2012 with respect to site of diagnosis and stage of HIV infection.

designSingle-centre observational cohort study.

settingAn outpatient HIV department in a secondary care UK hospital.

participants1359 HIV-infected adults.

main outcome measuresDemographic information (age, gender, ethnicity, and sexual orientation), site of initial HIV diagnosis (Routine settings such as HIV/GUM clinics versus Non-Routine settings such as primary care and community venues), stage of HIV infection, CD4 count and seroconversion symptoms were collated for each participant.

resultsThere was a significant increase in the proportion of new HIV diagnoses made in Non-Routine settings (from 27.0% in 2000 to 58.8% in 2012; p<0.001). Overall there was a decrease in the rate of late diagnosis from 50.7% to 32.9% (p=0.001). Diagnosis of recent infection increased from 23.0% to 47.1% (p=0.001). Of those with recent infection, significantly more patients were likely to report symptoms consistent with a seroconversion illness over the 13 years (17.6% to 65.0%; p<0.001).

conclusionsThis is the first study, we believe, to demonstrate significant improvements in HIV diagnosis and a shift in diagnosis of HIV from HIV/GUM settings to primary practice and community settings due to multiple initiatives.

Indexed as

AdultAIDS SerodiagnosisCohort StudiesCommunity Health ServicesFemaleHIV InfectionsHumansMalePrimary Health Care

Identifiers

PMID25885092
PMCPMC4401513
OpenAlexW2005399525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.