Evidence map›Paper›PMID 25885061›Full record

ArticleRadiation oncology (London, England)2015

A case of radiotherapy for an advanced bronchial carcinoma patient with implanted cardiac rhythm machines as well as heart assist device.

Sergiu Scobioala, Iris Ernst, Christos Moustakis, Uwe Haverkamp, Sven Martens, Hans Theodor Eich

Open access · goldAbstract readCase Reports
In one paragraph

Article in Radiation oncology (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sergiu ScobioalaDepartment of Radiotherapy and Radiooncology, University Hospital of Muenster, Muenster, 48149, Germany. Sergiu.Scobioala@ukmuenster.de.
Iris ErnstDepartment of Radiotherapy and Radiooncology, University Hospital of Muenster, Muenster, 48149, Germany. Iris.Ernst@ukmuenster.de.
Christos MoustakisDepartment of Radiotherapy and Radiooncology, University Hospital of Muenster, Muenster, 48149, Germany. Christos.Moustakis@ukmuenster.de.
Uwe HaverkampDepartment of Radiotherapy and Radiooncology, University Hospital of Muenster, Muenster, 48149, Germany. uwe.haverkamp@ukmuenster.de.
Sven MartensDepartment of cardiac and thoracic surgery, University Hospital of Muenster, Muenster, 48149, Germany. sven.martens@ukmuenster.de.
Hans Theodor EichDepartment of Radiotherapy and Radiooncology, University Hospital of Muenster, Muenster, 48149, Germany. hans.eich@ukmuenster.de.
University Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of radiotherapy for a 66-year-old patient with squamous cell carcinoma on the left main bronchus undergoing implantation of pacemaker, implantable cardioverter defibrillator (ICD) as well as cardiopulmonary support (CPS) device. The radiation area was determined according to 4D List Mode positron emission tomography-computed tomography (PET-CT) data. Planning Target Volume (PTV) included a part of the active ICD. For the optimal tumor coverage and sparing of both the implantable cardiac devices and organs at risk, we combined the conformal radiotherapy with stereotactic body radiotherapy (SBRT) using helical tomotherapy. The prescription dose of 25.2Gy was applied by conventional radiotherapy. SBRT was performed hypofractionated with a prescription dose of 35Gy in 5 fractions. A dynamic electrocardiogram was performed during every radiation fraction. The implanted aggregates were checked three times a week. Despite partial localization of the active ICD in the radiation field, the tumor was treated without inappropriate shock delivery during radiation treatment and over twelve months afterwards. The reduced tumor size as well as tumor metabolic activity were observed by PET-CT three months after radiation treatment. The patient exhibited no signs of pneumonitis on the last radiological follow-up examination six months after radiotherapy. The reduced dyspnea and cough over the first four months after treatment were observed.In conclusion, tumor shrinkage and temporary clinical improvement of the patient as well as no technical complications of implanted cardiac devices were achieved by the radiation treatment.

Indexed as

Heart-Assist DevicesPacemaker, ArtificialRadiosurgeryAgedCarcinoma, BronchogenicCarcinoma, Squamous CellHumansMalePositron-Emission TomographyRadiotherapy, ConformalTomography, X-Ray ComputedTreatment Outcome

Identifiers

PMID25885061
PMCPMC4389884
OpenAlexW2153865369

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.