Trial reportImplementation science : IS2015
Assisted partner notification services to augment HIV testing and linkage to care in Kenya: study protocol for a cluster randomized trial.
Trial report in Implementation science : IS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01616420 (Assisted Partner Notification to Augment HIV Treatment and Prevention in Kenya), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assisted Partner Notification to Augment HIV Treatment and Prevention in Kenya
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- A Review of the Ring Trial Design for Evaluating Ring Interventions for Infectious Diseases.Epidemiologic reviews · 2022Pooled it
- Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya.Sexually transmitted diseases · 2020Trial
- Index participant characteristics and HIV assisted partner services efficacy in Kenya: results of a cluster randomized trial.Journal of the International AIDS Society · 2019Trial
- Brief Report: HIV Assisted Partner Services Among Those With and Without a History of Intimate Partner Violence in Kenya.Journal of acquired immune deficiency syndromes (1999) · 2018Trial
- Assisted partner notification services are cost-effective for decreasing HIV burden in western Kenya.AIDS (London, England) · 2018Trial
- Assisted partner services for HIV in Kenya: a cluster randomised controlled trial.The lancet. HIV · 2017Trial
- Understanding Barriers to Scaling Up HIV-Assisted Partner Services in Kenya.AIDS patient care and STDs · 2016Trial
- HIV assisted partner services (aPS) to support integrated HIV and hypertension screening in Kenya: a pre-post intervention study.BMC public health · 2023Article
- Knowledge, attitudes, and practices of healthcare workers regarding human immunodeficiency virus index testing in 2021, Burkina Faso.Journal of public health in Africa · 2023Article
- Implementation fidelity to HIV assisted partner services (aPS) during scale-up in western Kenya: a convergent mixed methods study.BMC health services research · 2023Article
- Integration of assisted partner services within Kenya's national HIV testing services program: A qualitative study.PLOS global public health · 2023Article
- Article
- The practice of pilot/feasibility studies in informing the conduct of HIV related clinical trials in sub-Saharan Africa: A scoping review.Contemporary clinical trials communications · 2022Article
- Cost of integrating assisted partner services in HIV testing services in Kisumu and Homa Bay counties, Kenya: a microcosting study.BMC health services research · 2022Article
- Assessment of Index Case Family Testing Among Adults Attending Art Clinic at Kule Refugee Camp, Southwest Ethiopia: 2021.HIV/AIDS (Auckland, N.Z.) · 2022Article
- Low partner testing in high HIV prevalence setting in Freetown, Sierra Leone: a retrospective study.BMC research notes · 2019Article
- Enhancing an HIV index case testing passive referral model through a behavioural skills-building training for healthcare providers: a pre-/post-assessment in Mangochi District, Malawi.Journal of the International AIDS Society · 2019Article
- Assisted HIV partner services training in three sub-Saharan African countries: facilitators and barriers to sustainable approaches.Journal of the International AIDS Society · 2019Article
- Low risk of social harms in an HIV assisted partner services programme in Cameroon.Journal of the International AIDS Society · 2019Article
- HIV Partner Notification Across Different Sexual Partner Types Among Men Who Have Sex with Men in Guangzhou, China.AIDS patient care and STDs · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundHIV case-finding and linkage to care are critical for control of HIV transmission. In Kenya, >50% of seropositive individuals are unaware of their status. Assisted partner notification is a public health strategy that provides HIV testing to individuals with sexual exposure to HIV and are at risk of infection and disease. This parallel, cluster-randomized controlled trial will evaluate the effectiveness, cost-effectiveness, and feasibility of implementing HIV assisted partner notification services at HIV testing sites (clusters) in Kenya. METHODS/
designEighteen sites were selected among health facilities in Kenya with well-established, high-volume HIV testing programs, to reflect diverse communities and health-care settings. Restricted randomization was used to balance site characteristics between study arms (n = 9 per arm). Sixty individuals testing HIV positive ('index partners') will be enrolled per site (inclusion criteria: ≥18 years, positive HIV test at a study site, willing to disclose sexual partners, and never enrolled for HIV care; exclusion criteria: pregnancy or high risk of intimate partner violence). Index partners provide names and contact information for all sexual partners in the past 3 years. At intervention sites, study staff immediately contact sexual partners to notify them of exposure, offer HIV testing, and link to care if HIV seropositive. At control sites, passive partner referral is performed according to national guidelines, and assisted partner notification is delayed by 6 weeks. Primary outcomes, assessed 6 weeks after index partner enrollment and analyzed at the cluster level, are the number of partners accepting HIV testing and number of HIV infections diagnosed and linked to care per index partner. Secondary outcomes are the incremental cost-effectiveness of partner notification and the costs of identifying >1 partner per index case. Participants are closely monitored for adverse outcomes, particularly intimate partner violence. The study is unblinded due to practical limitations. DISCUSSION: This rigorously designed trial will inform policy decisions regarding implementation of HIV partner notification services in Kenya, with possible application to other parts of sub-Saharan Africa. Examination of effectiveness and cost-effectiveness in diverse settings will enable targeted application and define best practices.
trial registrationClinicalTrials.gov NCT01616420 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.