Trial reportImplementation science : IS2015
Effectiveness of a tailored implementation programme to improve recognition, diagnosis and treatment of anxiety and depression in general practice: a cluster randomised controlled trial.
Trial report in Implementation science : IS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Tailored interventions to address determinants of practice.The Cochrane database of systematic reviews · 2026Pooled it
- Audit and feedback: effects on professional practice.The Cochrane database of systematic reviews · 2025Pooled it
- Effectiveness of late-life depression interventions on functional limitations: A systematic review.International journal of mental health nursing · 2022Pooled it
- Elusive search for effective provider interventions: a systematic review of provider interventions to increase adherence to evidence-based treatment for depression.Implementation science : IS · 2018Pooled it
- Systematic Review and Meta-analysis of the Effectiveness of Implementation Strategies for Non-communicable Disease Guidelines in Primary Health Care.Journal of general internal medicine · 2018Pooled it
- Effects of collaborative care on recognition and management of common mental disorders by general practitioners: a cluster-randomised trial in Norway.BMC primary care · 2026Trial
- Implementing work-related Mental-health guidelines in general PRacticE (IMPRovE): findings of a parallel cluster randomised controlled trial.BMJ mental health · 2025Trial
- Effectiveness of Self-guided Tailored Implementation Strategies in Integrating and Embedding Internet-Based Cognitive Behavioral Therapy in Routine Mental Health Care: Results of a Multicenter Stepped-Wedge Cluster Randomized Trial.Journal of medical Internet research · 2023Trial
- Process evaluation of a cluster randomised intervention in Swedish primary care: using care managers in collaborative care to improve care quality for patients with depression.BMC family practice · 2019Trial
- A tailored intervention to implement guideline recommendations for elderly patients with depression in primary care: a pragmatic cluster randomised trial.Implementation science : IS · 2016Trial
- Intraclass correlation in cluster randomized controlled trials for anxiety disorders: Evidence from a meta-analysis.Indian journal of psychiatry · 2026Article
- Effect of a needs-based model of care on the characteristics of healthcare services in England: the i-THRIVE National Implementation Programme.Epidemiology and psychiatric sciences · 2025Article
- A mixed-methods observational study of strategies for success in implementation science: overcoming emergency departments hurdles.BMC health services research · 2025Observational
- Advancing Global Health Through Primary Care Physician Education on Suicide Prevention.Annals of global health · 2024Review
- A multifaceted provider-centred intervention versus usual care to improve the recognition and diagnosis of depression in primary health care: a hybrid study.Primary health care research & development · 2023Article
- Consumer Perspectives on Anxiety Management in Australian General Practice.International journal of environmental research and public health · 2022Article
- General practitioners' perspectives on barriers to depression care: development and validation of a questionnaire.BMC family practice · 2020Article
- A typology of useful evidence: approaches to increase the practical value of intervention research.BMC medical research methodology · 2020Article
- Can the Use of Bayesian Analysis Methods Correct for Incompleteness in Electronic Health Records Diagnosis Data? Development of a Novel Method Using Simulated and Real-Life Clinical Data.Frontiers in public health · 2020Article
- Care managers can be useful for patients with depression but their role must be clear: a qualitative study of GPs' experiences.Scandinavian journal of primary health care · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnxiety and depression are not always diagnosed and treated in primary care as has been recommended. A tailored implementation programme, which addresses key barriers for change by targeted interventions, may help to remedy this.
methodsThe effectiveness of an individually tailored implementation programme, additional to standardised training and feedback on the recognition and treatment of patients with anxiety or depression in general practice, was examined in a cluster randomised controlled trial. Participants were 46 general practitioners (GPs) from 23 general practices (12 intervention, 11 control) and 444 patients aged 18 years or older (198 intervention, 246 control) who screened positive on the extended Kessler 10. In the control group, GPs received a 1-day training in guidelines for recognition and stepped treatment for anxiety and depression. Ten months after the training session, GPs received feedback on their performance over the preceding 6 months. In the intervention group, GPs received the same training and feedback as those in the control condition; in addition, they were offered support, tailored to perceived local barriers to change. The support was delivered in the format of peer group supervisions and personalised telephone consultations. Data were based on an audit of patient records and patient surveys at baseline and after 3 and 6 months.
resultsThe tailored implementation programme led to recognition of a higher proportion of patients presenting with anxiety and depression (42% versus 31%; odds ratio (OR) = 1.60; 95% CI: 1.01-2.53), more consultations after recognition (IRR = 1.78; 95% CI: 1.14-2.78) and did not lead to more prescription of antidepressants (OR = 1.07; 95% CI: 0.52-2.19) or referral to specialist mental health services (OR = 1.62; 95% CI: 0.72-3.64). Patients in the intervention group reported better accessibility of care (effect size (ES) = 0.4; p < 0.05) and provision of information and advice (ES = 0.5; p < 0.05).
conclusionsA tailored implementation programme may enhance the recognition and treatment of patients with anxiety or depression. Further development and evaluation of the programme is warranted to determine its cost-effectiveness. TRAIL REGISTRATION: Dutch Trial Register identifier NTR1912 .
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.