Evidence map›Paper›PMID 25884693›Full record

ArticleBMC research notes2015

Complete heart block in dengue complicating management of shock due to both bleeding and leakage: a case report.

Mitrakrishnan Rayno Navinan, Jevon Yudhishdran, Sandamalee Herath, Isurujith Liyanage, Tharshana Kugadas, Damith Kumara, Aruna Kulatunga

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Dengue and the heart.Cardiovascular journal of Africa
    Pooled it
  2. Article
  3. Case Report and Review of the Literature: Ischemic Stroke in Dengue Virus Infection.The American journal of tropical medicine and hygiene · 2024
    Review
  4. Article
  5. Mechanism of Immune Evasion in Mosquito-Borne Diseases.Pathogens (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mitrakrishnan Rayno NavinanNational Hospital of Sri Lanka, Colombo, Sri Lanka. rayno.navinan@gmail.com.
Jevon YudhishdranNational Hospital of Sri Lanka, Colombo, Sri Lanka. yudhishdran@yahoo.com.
Sandamalee HerathNational Hospital of Sri Lanka, Colombo, Sri Lanka. sandaherath@yahoo.com.
Isurujith LiyanageNational Hospital of Sri Lanka, Colombo, Sri Lanka. isurujith@gmail.com.
Tharshana KugadasNational Hospital of Sri Lanka, Colombo, Sri Lanka. ktharshana@gmail.com.
Damith KumaraNational Hospital of Sri Lanka, Colombo, Sri Lanka. daam293@gmail.com.
Aruna KulatungaNational Hospital of Sri Lanka, Colombo, Sri Lanka. kulatunga.aruna@yahoo.com.
National Hospital of Sri Lanka · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe spread of Dengue virus infection is reaching pandemic proportions. Dengue is usually dreaded for causing shock due to capillary leakage. However the clinical spectrum of dengue is vast and the newly incorporated expanded dengue syndrome introduces a wide range of presentations that are rarely observed and appreciated but nevertheless have the potential to cause significant morbidity and even mortality. Cardiac involvement in dengue is one such example. CASE PRESENTATION: A 26 year old South-Asian female presented in a state of haemodynamic shock with a history of fever and use of non-steroidal anti inflammatory drugs. Dengue was suspected clinically and later confirmed. Following stabilization and while still in the febrile phase the patient developed bradycardia with dynamic electrocardiogram changes which evolved into complete heart block. However there was no circulatory compromise. Clinical picture was further complicated by the development of dengue haemorhaghic fever and cautious fluid resuscitation was carried out in correlation to clinical and haematological parameters. Impaired coagulation profile necessitated administration of activated factor seven on the backdrop of low platelets and bleeding. Cardiac pacing could be avoided due to maintenance of vitals within acceptable parameters.

conclusionExpanded dengue syndrome should be given greater appreciation as not all may be benign. Cardiovascular system involvement in dengue has the potential to cause significant morbidity and mortality. Careful interpretation of clinical parameters will help in the institution of the appropriate management and help avoid unnecessary invasive interventions. Screening of dengue patients with timely electrocardiographs would be useful to detect cardiac involvement. Guidance on managing atypical manifestations of dengue expanded syndrome should available to help clinicians dictate treatment.

Indexed as

AdultBradycardiaDengue VirusDisease ManagementFactor VIIaFemaleFeverFluid TherapyHeartHeart BlockHemorrhageHumansSevere DengueFactor VIIa

Identifiers

PMID25884693
PMCPMC4351841
OpenAlexW2085650152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.