ArticleParticle and fibre toxicology2015
Size-fractioned ultrafine particles and black carbon associated with autonomic dysfunction in subjects with diabetes or impaired glucose tolerance in Shanghai, China.
Article in Particle and fibre toxicology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Health effects of ultrafine particles: a systematic literature review update of epidemiological evidence.International journal of public health · 2019Pooled it
- Psychosocial Stress Modifies the Acute Cardiac Health Effects of Traffic-Related Air Pollution.Environment & health (Washington, D.C.) · 2024Article
- Adverse Effects of Prenatal Exposure to Oxidized Black Carbon Particles on the Reproductive System of Male Mice.Toxics · 2023Article
- Particle Number Concentration Measurements on Public Transport in Bangkok, Thailand.International journal of environmental research and public health · 2023Article
- Ambient air pollution associated with incidence and dynamic progression of type 2 diabetes: a trajectory analysis of a population-based cohort.BMC medicine · 2022Article
- Short-Term Associations between Size-Fractioned Particles and Cardiopulmonary Function in COPD Patients: A Panel Study in Shanghai, China, during 2014-2021.International journal of environmental research and public health · 2022Article
- Xenobiotics Delivered by Electronic Nicotine Delivery Systems: Potential Cellular and Molecular Mechanisms on the Pathogenesis of Chronic Kidney Disease.International journal of molecular sciences · 2022Review
- Effect of short-term exposure to particulate air pollution on heart rate variability in normal-weight and obese adults.Environmental health : a global access science source · 2021Article
- The health effects of ultrafine particles.Experimental & molecular medicine · 2020Review
- Heart rate variability and cardiac repolarization after exposure to zinc oxide nanoparticles in healthy adults.Journal of occupational medicine and toxicology (London, England) · 2020Article
- Impact of Commuting Mode on Obesity Among a Working Population in Beijing, China: Adjusting for Air Pollution.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Hourly Exposure to Ultrafine Particle Metrics and the Onset of Myocardial Infarction in Augsburg, Germany.Environmental health perspectives · 2020Article
- Synthesis of Harvard Environmental Protection Agency (EPA) Center studies on traffic-related particulate pollution and cardiovascular outcomes in the Greater Boston Area.Journal of the Air & Waste Management Association (1995) · 2019Article
- Susceptibility of prediabetes to the health effect of air pollution: a community-based panel study with a nested case-control design.Environmental health : a global access science source · 2019Article
- Exposure to Atmospheric Ultrafine Particles Induces Severe Lung Inflammatory Response and Tissue Remodeling in Mice.International journal of environmental research and public health · 2019Article
- Ambient and controlled exposures to particulate air pollution and acute changes in heart rate variability and repolarization.Scientific reports · 2019Article
- An easily ignored factor for CAN-fine particulate exposure [Letter].Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge.Environmental health perspectives · 2017Review
- Occupational exposures and determinants of ultrafine particle concentrations during laser hair removal procedures.Environmental health : a global access science source · 2017Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundParticles in smaller size fractions, such as ultrafine particles (UFPs) (with diameter less than 100 nm), has become of significant cardiovascular health concerns. However, the biological plausibility underlying potential relationship between UFPs and cardiovascular outcomes is less studied.
methodsFifty-three subjects living in Shanghai with type-2 diabetes (T2D) or impaired glucose tolerance (IGT) were followed for autonomic dysfunctions with three repeated measurements in 2010. Minute-to-minute concentrations of ambient particles in small size-fractions (5-560 nm), black carbon (BC), sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and ozone (O3) were monitored using a central monitoring laboratory equipped with real-time air monitors close to residential area of the subjects. Generalized linear mixed models, with adjustment for individual risk factors, were applied to assess the effects of air pollution on autonomic dysfunctions in subjects.
resultsOur study showed that significant reduction in the standard deviation of all NN intervals (SDNN) ranging from 3.4% to 8.1% were associated with interquartile range (IQR) increase of number concentration of particles (PNC) in size fractions<100 nm, and reduction from 1.3% to 4.6% with particles of diameter 100-200 nm, in subjects with diabetes or glucose tolerance. Increased exposure to traffic-related pollutants BC, NO2 and CO, and combustion pollutant SO2, were also significantly associated with HRV reductions. However, no effect was observed for particles in size fraction of 200-560 nm and O3. Diabetic risk factor and gender appeared to have significant interactions on autonomic dysfunction associated with UFPs and traffic pollution exposures in certain time-window.
conclusionsOur results suggest that underlying diabetes or impaired glucose tolerance may confer reduced autonomic function of heart due to traffic pollution exposure.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.