Evidence map›Paper›PMID 25884223›Full record

Trial reportBMC psychiatry2015

A multi-site randomized study to compare the effects of Eye Movement Desensitization and Reprocessing (EMDR) added to TAU versus TAU to reduce craving and drinking behavior in alcohol dependent outpatients: study protocol.

Wiebren Markus, Gerdien H de Weert-van Oene, Eni S Becker, Cor A J DeJong

2 registry-linked trialsOpen access · goldAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01828866 nacompletednot on this map

From Feasibility to Efficacy: the Use of EMDR to Reduce Craving and Drinking Behaviour in Alcohol Dependent Outpatients - A Multiple Baseline Study and Randomized Controlled Trial (RCT)

TypeinterventionalSponsorIrisZorgRan2013 to 2016Enrolled109ConditionsAlcohol DependenceArmsEMDR, Community Reinforcement Approach
NCT05606900 nacompletednot on this mapstarted 2022, after this paper: background citation

Eye Movements Desensitization and Reprocessing (EMDR) Intervention in Preventing Craving in Alcohol Use Disorder: Randomized Controlled Study

TypeinterventionalSponsorEge UniversityRan2022 to 2023Enrolled24ConditionsAlcohol Use Disorder, Alcohol CravingArmsaddiction-focused eye movements desensitization and reprocessing (AF-EMDR)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Wiebren MarkusIrisZorg, Institute for Addiction Care, Sheltered Housing and Social Support Services, Kronenburgsingel 545, P.O. box 351, 6800 AJ, Arnhem, Netherlands. w.markus@iriszorg.nl.
Gerdien H de Weert-van OeneNijmegen Institute for Scientist-Practitioners in Addiction (NISPA), Radboud Universiteit Nijmegen/ACSW, P.O. box 9104, 6500 HE, Nijmegen, Netherlands. gdweert@victas.nl.
Eni S BeckerBehavioral Science Institute (BSI), Radboud University Nijmegen, P.O. box 9104, 6500 HE, Nijmegen, The Netherlands. e.becker@psych.ru.nl.
Cor A J DeJongNijmegen Institute for Scientist-Practitioners in Addiction (NISPA), Radboud Universiteit Nijmegen/ACSW, P.O. box 9104, 6500 HE, Nijmegen, Netherlands. nispa.dejong@gmail.com.
Nijmegen Institute for Scientist Practitioners in Addiction · NLIrisZorg · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAddiction constitutes a major public health problem, and despite treatment, relapse rates remain very high. Preliminary findings suggest that Eye Movement Desensitization and Reprocessing (EMDR), an evidence-based treatment for PTSD, may also reduce craving and relapse rates when applied in substance abuse. This study aims to determine the feasibility, efficacy and effectiveness of EMDR when added to treatment as usual (TAU) for addiction in alcohol dependent outpatients, compared to TAU only. METHODS/

designA single blinded study in which 100 adult patients with a primary DSM-IV-TR diagnosis of alcohol dependence or abuse receiving treatment in one of six Dutch outpatient addiction care facility sites, will be enrolled. After baseline assessment participants will be allocated to one of two treatment conditions (allocation ratio of 1:1) using a stratified (per site, per care pathway), blocked randomization procedure. The intervention consists of EMDR (seven weekly 90 minute sessions) + TAU or TAU only. Assessments are scheduled pre-treatment (t0), post-treatment (t0 + eight weeks), and one and six months post treatment. The effects of both treatment arms are compared on indices of (a) drinking behavior, (b) mediators, moderators and predictors of treatment outcome, (c) quality of life and d) safety, acceptability and feasibility of treatment. Repeated measures ANOVA's will be conducted using an intention-to-treat and per-protocol approach. Multiple imputation will be used to deal with missing values when possible. DISCUSSION: This study adapts and extends the standard EMDR treatment for traumatized patients for use with patients with alcohol use disorders without psychological trauma.

trial registrationClinicalTrial.gov: NCT01828866.

Indexed as

AdolescentAdultAgedAlcohol DrinkingAlcoholismAmbulatory CareAnalysis of VarianceChronic DiseaseClinical ProtocolsCombined Modality TherapyCravingEye Movement Desensitization ReprocessingFemaleHumansMaleMiddle Aged

Identifiers

PMID25884223
PMCPMC4369870
OpenAlexW2146478539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.