ArticleBMC health services research2015
Validation of the Adherence Barriers Questionnaire - an instrument for identifying potential risk factors associated with medication-related non-adherence.
Article in BMC health services research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 5 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Measurement Properties of Patient-Reported Outcome Measures for Medication Adherence in Cardiovascular Disease: A COSMIN Systematic Review.Clinical drug investigation · 2022Pooled it
- Patient-reported outcome measures to detect intentional, mixed, or unintentional non-adherence to medication: a systematic review.BMJ open · 2022Pooled it
- Measurement Properties of Existing Patient-Reported Outcome Measures on Medication Adherence: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Development of an Item Bank to Measure Medication Adherence: Systematic Review.Journal of medical Internet research · 2020Pooled it
- A systematic review of dimensions evaluating patient experience in chronic illness.Health and quality of life outcomes · 2019Pooled it
- Comparison of a new 3-item self-reported measure of adherence to medication with pharmacy claims data in patients with cardiometabolic disease.American heart journal · 2020Trial
- Article
- Cultural adaptation and psychometric validation of the Amharic adherence barriers questionnaire for HIV patients on antiretroviral therapy in Ethiopia.Scientific reports · 2026Article
- Article
- Medication-related burden variation across chronic conditions: a population-based cross-sectional survey.BMC health services research · 2025Article
- Adherence Barriers, Patient Satisfaction, and Depression in Albanian Ambulatory Patients.Healthcare (Basel, Switzerland) · 2025Article
- Article
- Medication adherence scales in non-communicable diseases: A scoping review of design gaps, constructs and validation processes.PloS one · 2025Article
- Chinese translation validation of the adherence barrier questionnaire (intravitreal anti-vascular endothelial growth factor therapy) in Taiwan.The Kaohsiung journal of medical sciences · 2024Article
- Medication adherence in geriatric patients attending medical outpatient department.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024Article
- Adaptation and validation of the Adherence Barriers Questionnaire for HIV Patients on Antiretroviral Therapy (ABQ-HIV) for the Brazilian context.Cadernos de saude publica · 2024Article
- Developing a Suite of Resources to Improve Patient Adherence to Compression Stockings: Application of Behavior Change Theory.Patient preference and adherence · 2023Article
- Māori, pharmacists, and medicines adherence - A mixed methods study exploring indigenous experiences of taking medicines 'as prescribed' and mechanisms of support.Exploratory research in clinical and social pharmacy · 2022Article
- Article
- The PostStroke-Manager - combining mobile, digital and sensor-based technology with personal assistance: protocol of the feasibility study.Neurological research and practice · 2021Article
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3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMedication non-adherence is a major challenge in the real-life treatment of chronically ill patients. To meet this challenge, adherence interventions with a tailored approach towards patient-specific adherence barriers that are identified with a reliable and practicable questionnaire are needed. The aim of this investigation was to develop and validate such a questionnaire, the "Adherence Barriers Questionnaire (ABQ)".
methodsThe German ABQ was developed and tested in 432 patients with atrial fibrillation in a multicentre observational cohort study. Evaluation of the questionnaire included an assessment of internal consistency as well as factor analysis. Criterion-related external validity was assessed by comparing the ABQ score with (1) the degree of self-reported adherence and (2) the time in therapeutic range which describes the anticoagulation quality achieved by patients treated with oral anticoagulation.
resultsThe final 14-item ABQ scale demonstrated high internal consistency (Cronbach's alpha = 0.820). Factor analysis identified a three-factor solution, representing intentional adherence barriers with 5 items (31.9% of the variance), medication-/health care system-related adherence barriers with 5 items (13.3% of the variance) and unintentional adherence barriers with 4 items (7.7% of the variance). The ABQ correlated significantly with self-reported non-adherence (Spearman's rho = 0.438, p < 0.001) as well as time in therapeutic range (Spearman's rho = - 0.161, p < 0.010). Patients with above-average ABQ scores (increased number and/or strength of existing adherence barriers) were significantly (p < 0.005, Pearson Chi-Square) more likely to have a poor anticoagulation quality (TTR < 60%) than patients with a lower ABQ score (44.6% versus 27.3%).
conclusionsThe ABQ is a practicable, reliable and valid instrument for identifying patient-specific barriers to medication-related adherence. Future research is required to examine the ability of the ABQ to identify patient perception/behaviour changes over time which may be important for the measurement of success of adherence interventions.
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