Evidence map›Paper›PMID 25884182›Full record

ArticleBMC public health2015

Impact of unstable housing on all-cause mortality among persons who inject drugs.

Rebecca Zivanovic, M J Milloy, Kanna Hayashi, Huiru Dong, Christy Sutherland, Thomas Kerr, Evan Wood

Abstract read
In one paragraph

Article in BMC public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rebecca ZivanovicBritish Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, 608-1081 Burrard St, Vancouver, BC, V6Z 1Y6, Canada. rebecca.gordon@alumni.ubc.ca.
M J MilloyBritish Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, 608-1081 Burrard St, Vancouver, BC, V6Z 1Y6, Canada. uhri-mjsm@cfenet.ubc.ca.
Kanna HayashiBritish Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, 608-1081 Burrard St, Vancouver, BC, V6Z 1Y6, Canada. khayashi@cfenet.ubc.ca.
Huiru DongBritish Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, 608-1081 Burrard St, Vancouver, BC, V6Z 1Y6, Canada. hdong@cfenet.ubc.ca.
Christy SutherlandBritish Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, 608-1081 Burrard St, Vancouver, BC, V6Z 1Y6, Canada. dr.christy.sutherland@gmail.com.
Thomas KerrBritish Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, 608-1081 Burrard St, Vancouver, BC, V6Z 1Y6, Canada. uhri-tk@cfenet.ubc.ca.
Evan WoodBritish Columbia Centre for Excellence in HIV/AIDS, St Paul's Hospital, 608-1081 Burrard St, Vancouver, BC, V6Z 1Y6, Canada. uhri-ew@cfenet.ubc.ca.

Funding

Vancouver Drug Users Study: The Impacts of Evolving Drug Use Patterns on HIV/AIDSU01DA038886 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI DEBECK, KORA, HAYASHI, KANNA · 2015 to 2024
$12.1M
SYRINGE ACCESS AND RISK FACTORS ON HIV TRANSMISSIONR01DA011591 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI KERR, THOMAS · 1998 to 2014
$5.9M
Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersR01DA021525 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI MILLOY, M-J · 2007 to 2016
$5.8M
NIDA NIH HHS R01 DA011591NIDA NIH HHS R01DA011591NIDA NIH HHS R01 DA021525NIDA NIH HHS R01DA021525NIDA NIH HHS U01 DA038886
6 · The paper itself

Abstract

backgroundIllicit drug injecting is a well-established risk factor for morbidity and mortality. However, a limited number of prospective studies have examined the independent effect of unstable housing on mortality among persons who inject drugs (PWIDs). In this study we sought to identify if a relationship exists between unstable housing and all-cause mortality among PWIDs living in Vancouver, Canada.

methodsPWIDs participating in two prospective cohort studies in Vancouver, Canada were followed between May 1996 and December 2012. Cohort data were linked to the provincial vital statistics database to ascertain mortality rates and causes of death. We used multivariate Cox proportional hazards regression to determine factors associated with all-cause mortality and to investigate the independent relationship between unstable housing and time to all-cause mortality.

resultsDuring the study period, 2453 individuals were followed for a median of 69 months (Inter-quartile range [IQR]: 34 - 113). In total, there were 515 (21.0%) deaths for an incidence density of 3.1 (95% Confidence Interval [CI]: 2.8 - 3.4) deaths per 100 person years. In multivariate analyses, after adjusting for potential confounders including HIV infection and drug use patterns, unstable housing remained independently associated with all-cause mortality (adjusted hazard ratio [AHR] = 1.30, 95% CI: 1.08 - 1.56).

conclusionsThese findings demonstrate that unstable housing is an important risk factor for mortality independent of known risk factors including HIV infection and patterns of drug use. This study highlights the urgent need to provide supportive housing interventions to address elevated levels of preventable mortality among this population.

Indexed as

AdultCanadaDatabases, FactualFemaleHousingHumansIncidenceMaleMiddle AgedMorbidityMultivariate AnalysisProspective StudiesRisk FactorsSubstance Abuse, Intravenous

Identifiers

PMID25884182
PMCPMC4389703

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.