ArticleBMC infectious diseases2015
Syphilis among people with HIV infection in southern Ethiopia: sero-prevalence and risk factors.
Article in BMC infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 32 citations in OpenAlex.
- Investigating latent syphilis in HIV treatment-experienced Ethiopians and response to therapy.PloS one · 2022Trial
- Prevalence and risk factors of hepatitis B, hepatitis C, and syphilis among reproductive-age adults in the Tigray region, Northern Ethiopia: a community-based cross-sectional study.Scientific reports · 2026Article
- Diagnostic performance evaluation of the Abbott Bioline™ HIV/Syphilis Duo rapid test at the national public health laboratory, Yaounde-Cameroon.BMC infectious diseases · 2026Article
- Seroprevalence of syphilis and associated factors among pregnant women who attended antenatal care follow-up at public hospitals in Bahir Dar city, north-west Ethiopia: a cross-sectional study.BMJ public health · 2025Article
- Sero-prevalence of syphilis infection among people living with HIV in Sierra Leone: a cross-sectional nationwide hospital-based study.BMC infectious diseases · 2023Article
- Magnitude and Determinants of Syphilis and HIV Co-Infection Among Female Sex Workers in Ethiopia: Evidence from Respondent Driven Samples, 2019-2020.HIV/AIDS (Auckland, N.Z.) · 2022Article
- Using a dual antibody point-of-care test with visual and digital reads to diagnose syphilis among people living with HIV in Botswana.International journal of STD & AIDS · 2021Article
- A Comparative Study of the Epidemiology of Treponemal Infection in the Volta and Oti Regions of Ghana: A Five-Year Multisite Parallel Population-Based Analysis vis-à-vis the Sentinel Survey.BioMed research international · 2021Article
- Article
- Clean and Safe Healthcare Environment: Knowledge, Attitude, and Practice of Infection Prevention and Control among Health Workforce at North Showa Zone Oromiya Region.Journal of environmental and public health · 2020Article
- The epidemiology of syphilis in Ethiopia: a protocol for systematic review and meta-analysis covering the last three decades.Systematic reviews · 2019Article
- Neurological disorders in HIV in Africa: a review.African health sciences · 2019Review
- Factors associated with syphilis infection: a cross-sectional survey among outpatients in Asikuma Odoben Brakwa District, Ghana.BMC infectious diseases · 2019Article
- Seroprevalence of syphilis and its risk factors among pregnant women attending antenatal care at Felege Hiwot Referral Hospital, Bahir Dar, northwest Ethiopia: a cross-sectional study.BMC research notes · 2019Article
- High seroprevalence of syphilis infection among pregnant women in Yiregalem hospital southern Ethiopia.BMC infectious diseases · 2018Article
- An Update on the Global Epidemiology of Syphilis.Current epidemiology reports · 2018Article
- Coinfections with hepatitis B and C virus and syphilis among HIV-infected clients in Southern Ethiopia: a cross-sectional study.HIV/AIDS (Auckland, N.Z.) · 2017Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSyphilis facilitates both HIV (human immunodeficiency virus) transmission and acquisition, reflecting the complex interplay between the two infections. Scarce information exists regarding syphilis epidemiology in Ethiopian context. Thus, this study determined the sero-prevalence of syphilis and associated risk factors in people with HIV infection.
methodsA cross-sectional study was conducted at Hawassa Referral Hospital, southern Ethiopia from January to May, 2014. A consecutive 993 HIV-infected participants were studied; but individuals under 15 years of age or treated for syphilis or those with a CD4+ T-cell count below 50 cells/μl were excluded. Structured questionnaires were used to collect data on socio-demography and potential risk factors for syphilis. Moreover, blood samples were collected from all participants and screened for syphilis using rapid plasma reagin (RPR) test, and those found sero-positive were confirmed using treponema pallidum haemagglutination assay (TPHA).
resultsThe sero-prevalence of syphilis was found to be 7.3% (95% CI 5.7- 9%). The rate of infection was significantly higher among participants who were ART (antiretroviral therapy) naive (odds ratio (OR) = 2.2; 95% CI 1.22 - 4.1), men (OR = 2.2; 95% CI 1.22 - 3.87), older than 50 years of age (OR = 3.9; 95% CI 1.45 - 6.94), had only primary school level education (OR = 7.8; 95% CI 2.63 - 23.2) and had a history of blood transfusion (OR = 3.9; 95% CI 1.5 - 10.4).
conclusionThe high prevalence of syphilis among HIV-infected population warrants integrating syphilis screening with HIV care to limit the clinical consequences of untreated syphilis as well as its adverse impact on HIV transmission.
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