Evidence map›Paper›PMID 25884008›Full record

ArticleOpen forum infectious diseases2015

Implementing a large-scale systematic tuberculosis screening program in correctional facilities in South Africa.

Vincent Zishiri, Salome Charalambous, Maunank R Shah, Violet Chihota, Liesl Page-Shipp, Gavin J Churchyard, Christopher J Hoffmann

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Number needed to screen for TB in clinical, structural or occupational risk groups.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Article
  8. Article
  9. Determining the value of TB active case-finding: current evidence and methodological considerations.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2021
    Article
  10. Article
  11. Prevalence and risk factors of tuberculosis disease in South African correctional facilities in 2015.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2019
    Article
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vincent ZishiriThe Aurum Institute , Johannesburg , South Africa.
Salome CharalambousThe Aurum Institute , Johannesburg , South Africa ; School of Public Health , University of Witwatersrand , Johannesburg , South Africa.
Maunank R ShahSchool of Public Health , University of Witwatersrand , Johannesburg , South Africa.
Violet ChihotaThe Aurum Institute , Johannesburg , South Africa.
Liesl Page-ShippThe Aurum Institute , Johannesburg , South Africa.
Gavin J ChurchyardThe Aurum Institute , Johannesburg , South Africa ; School of Public Health , University of Witwatersrand , Johannesburg , South Africa.
Christopher J HoffmannThe Aurum Institute , Johannesburg , South Africa ; Johns Hopkins University School of Medicine , Baltimore, Maryland.

Funding

CAUSES OF AND ASSOCIATIONS WITH DEATH DURING LONG TERM HAART IN AFRICAK23AI083099 · NIAID · JOHNS HOPKINS UNIVERSITY · PI HOFFMANN, CHRISTOPHER J · 2010 to 2014
$671k
NIAID NIH HHS K23 AI083099
6 · The paper itself

Abstract

Background.  Tuberculosis (TB) prevalence is high in correctional facilities in southern Africa. With support from local South African nongovernmental organizations, the South African Department of Correctional Services initiated a program of systematically screening newly admitted and current inmates for symptoms followed by GeneXpert Mycobacterium tuberculosis (MTB)/rifampicin (Rif) for microbiologic testing of symptomatic inmates. Methods.  We conducted a program evaluation during a 5-month window describing program reach, effectiveness, adoption within the facilities, cost, and opportunities for sustainability. This evaluation included 4 facilities (2 large and 2 smaller) with a total daily census of 20 700 inmates. Results.  During the 5-month evaluation window from May to September 2013, 7426 inmates were screened at the 4 facilities. This represents screening 87% of all new admits (the remaining new admits were screened by correctional staff only and are not included in these statistics) and 23% of the daily inmate census, reaching 55% of the overall screening target as calculated per annum. The reach ranged from 57% screened during these 5 months at one of the smaller facilities to 13% at the largest facility. Two hundred one cases of pulmonary TB were diagnosed, representing 2.1% of the screened population; 93% had documented initiation of TB treatment. The cost per TB case identified was $1513, excluding treatment costs (with treatment costs it was $1880). Conclusions.  We reached a large number of inmates with high-volume screening and effectively used GeneXpert MTB/Rif to diagnose pulmonary TB and rapidly initiate treatment. The cost was comparable to other screening programs.

Indexed as

Africacorrectional facilityimplementationsystematic screeningtuberculosis

Identifiers

PMID25884008
PMCPMC4396427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.