ReviewJournal of diabetes research2015
Estrogen: an emerging regulator of insulin action and mitochondrial function.
Review in Journal of diabetes research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
107 citing papers in PubMed, 190 citations in OpenAlex.
- Cardiometabolic measures and cognition in early menopause - Analysis of baseline data from a randomized controlled trial.Maturitas · 2022Trial
- The gut microbiome drives inter- and intra-individual differences in metabolism of bioactive small molecules.Scientific reports · 2020Trial
- Association between diabetes and tinnitus traits in the UK Biobank: a population-based cohort study.Acta diabetologica · 2026Article
- Sex-Dependent and Asymmetric Associations of Bodyweight History in the Twenties with Later HbA1c Trajectories in a Japanese Occupational Cohort.Nutrients · 2026Article
- Association between dietary fat intake and fatty acid profiles and hyperuricemia among Chinese adults: Results from the China Health and Nutrition Survey.Asia Pacific journal of clinical nutrition · 2026Article
- Review
- Association between reproductive span and postmenopausal metabolic syndrome: a cross-sectional study in China.Menopause (New York, N.Y.) · 2026Article
- Early menarche and late menopause and their association with hypertension among Bangladeshi women: a community-based cross-sectional study in Dhaka, Bangladesh.BMC women's health · 2026Article
- Oral Toxicity Profile of a Novel Silk Lutein Extract and Assessment of Its Cardiovascular Benefits in Rodents.International journal of molecular sciences · 2026Article
- Sedentary behavior and type 2 diabetes in community-dwelling middle-aged and older adults: indirect cross-sectional correlation of sarcopenic obesity.Frontiers in endocrinology · 2026Article
- Dynamics of in-hospital body composition changes in mild and moderately severe acute pancreatitis: trajectories and predictors.Frontiers in nutrition · 2026Article
- Article
- Uterine and ovarian hemodynamics assessment of Camelus dromedarius with hormonal alterations and anatomical and histological architecture.Veterinary research communications · 2025Article
- Role of obesity and estrogen deficiency in non‑alcoholic fatty liver disease: Insights from a mouse model.Molecular medicine reports · 2025Article
- Sex Differences in Seasonal Variation in Metabolic Syndrome and Its Components: A 10-Year National Health Screening Study.Journal of clinical medicine · 2025Article
- Characterization of Turner Syndrome-associated Diabetes Mellitus.The Journal of clinical endocrinology and metabolism · 2025Article
- Metabolic Changes in Patients with Premature Ovarian Insufficiency: Adipose Tissue Focus-A Narrative Review.Metabolites · 2025Review
- A possible important regulatory role of estrogen in obstructive sleep apnea hypoventilation syndrome.Frontiers in medicine · 2025Review
- Triglyceride-glucose index is associated with lupus nephritis and gender disparity in systemic lupus erythematosus patients.Frontiers in medicine · 2025Article
- Sex hormone binding globulin (SHBG) modulates mitochondrial dynamics in PPARγ-depleted equine adipose derived stromal cells.Journal of molecular medicine (Berlin, Germany) · 2024Article
47 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Clinical trials and animal studies have revealed that loss of circulating estrogen induces rapid changes in whole body metabolism, fat distribution, and insulin action. The metabolic effects of estrogen are mediated primarily by its receptor, estrogen receptor-α; however, the detailed understanding of its mechanisms is incomplete. Recent investigations suggest that estrogen receptor-α elicits the metabolic effects of estrogen by genomic, nongenomic, and mitochondrial mechanisms that regulate insulin signaling, substrate oxidation, and energetics. This paper reviews clinical and experimental studies on the mechanisms of estrogen and the current state of knowledge regarding physiological and pathobiological influences of estrogen on metabolism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.