Evidence map›Paper›PMID 25883968›Full record

ArticleBioMed research international2015

Therapeutic effect of Agaricus brasiliensis on phenylhydrazine-induced neonatal jaundice in rats.

Lan Zhang, Bo Yuan, HuiPing Wang, Ya Gao

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Ameliorative Effect ofJournal of experimental pharmacology · 2024
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lan ZhangDepartment of Pediatrics, Second Hospital of Xi'an Jiaotong University, Xi'an 710004, China.
Bo YuanXi'an Central Hospital, Xi'an 710003, China.
HuiPing WangDepartment of Pediatrics, Second Hospital of Xi'an Jiaotong University, Xi'an 710004, China.
Ya GaoDepartment of Pediatrics, Second Hospital of Xi'an Jiaotong University, Xi'an 710004, China.
Second Affiliated Hospital of Xi'an Jiaotong University · CNFirst Hospital of Xi'an · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was designed to investigate the effect of Agaricus brasiliensis extract (ABE) on phenylhydrazine-induced neonatal jaundice in rats. Administration of ABE dose-dependently reduced the elevated bilirubin level induced by phenylhydrazine. It can be somewhat supported from the results of in vitro bilirubin degradation experiment. ABE treatment also reduced the total antioxidant status (TAOS), cascade O2(-)/SOD, level of NF-κB protein, and adrenomedullin (AM). Overall, the results of this study demonstrated that Agaricus brasiliensis extract may be beneficial to reducing bilirubin level without causing hepatotoxicity in neonatal jaundice.

Indexed as

Jaundice, NeonatalAdrenomedullinAgaricusAnimalsAntioxidantsComplex MixturesDisease Models, AnimalNF-kappa BPhenylhydrazinesRatsRats, WistarSuperoxide DismutaseSuperoxidesAdrenomedullinAntioxidantsComplex MixturesNF-kappa BphenylhydrazinePhenylhydrazinesSuperoxide DismutaseSuperoxides

Identifiers

PMID25883968
PMCPMC4389989
OpenAlexW1990830703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.