Evidence map›Paper›PMID 25883927›Full record

ArticleAnnals of pediatric endocrinology & metabolism2015

Relationship between serum 25-hydroxyvitamin D concentration and risks of metabolic syndrome in children and adolescents from Korean National Health and Nutrition Examination survey 2008-2010.

Dong Yup Lee, Ah Reum Kwon, Jung Min Ahn, Ye Jin Kim, Hyun Wook Chae, Duk Hee Kim, Ho-Seong Kim

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Article in Annals of pediatric endocrinology & metabolism, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

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12citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  9. Epidemiology of Childhood Obesity in Korea.Endocrinology and metabolism (Seoul, Korea) · 2016
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dong Yup LeeDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Ah Reum KwonDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Jung Min AhnDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Ye Jin KimDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Hyun Wook ChaeDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Duk Hee KimSowha Children's Hospital, Seoul, Korea.
Ho-Seong KimDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrevious studies have revealed many inconsistent results regarding the relationship between vitamin D and metabolic syndrome. The purpose of our study was to investigate the association between serum 25-hydroxyvitamin D (25(OH)D) concentration and factors that characterize metabolic syndrome in Korean children and adolescents.

methodsWe analyzed data from 2,880 children and adolescents aged 10-18 years collected from the 2008-2010 Korean National Health and Nutrition Examination Survey. We investigated the data according to quartiles of 25(OH)D concentrations.

resultsSystolic blood pressure and diastolic blood pressure with adjustment for sex and age differed significantly between the serum 25(OH)D groups and exhibited negative trend as 25(OH)D concentrations increased. The number of subjects with metabolic syndrome was greater in the low 25(OH)D groups (I, II, and III quartile) than in the high 25(OH)D group (IV quartile) (P=0.029). BMI and waist circumference were lower in the high 25(OH)D group. Serum 25(OH)D concentration correlated negatively with homeostasis model assessment estimate of insulin resistance (ρ=-0.073, P<0.001) and correlated positively with quantitative insulin sensitivity check index (ρ=0.095, P<0.001).

conclusionLow serum 25(OH)D level is associated with an increase of insulin resistance and metabolic syndrome in children and adolescents.

Indexed as

25-hydroxyvitamin DChildInsulin resistanceMetabolic syndromeObesity

Identifiers

PMID25883927
PMCPMC4397273

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.