Evidence map›Paper›PMID 25883535›Full record

ArticleCancer cell international2015

The role of death-associated protein 3 in apoptosis, anoikis and human cancer.

Umar Wazir, Mona Maw Orakzai, Zubair S Khanzada, Wen G Jiang, Anup K Sharma, Abdul Kasem, Kefah Mokbel

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer cell international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 32 citations in OpenAlex.

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  7. The role of the mitochondrial ribosomal protein family in detecting hepatocellular carcinoma and predicting prognosis, immune features, and drug sensitivity.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
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  9. Zonal interdependence in the temporomandibular joint cartilage.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  10. Article
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  13. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Umar WazirThe London Breast Institute, Princess Grace Hospital, London, UK ; Department of Breast Surgery, St. George's Hospital and Medical School, University of London, London, UK.
Mona Maw OrakzaiAyub Medical College, Abbottabad, Pakistan.
Zubair S KhanzadaMetastasis and Angiogenesis Research Group, University Department of Surgery, Cardiff University School of Medicine, Cardiff University, Cardiff, Wales UK.
Wen G JiangMetastasis and Angiogenesis Research Group, University Department of Surgery, Cardiff University School of Medicine, Cardiff University, Cardiff, Wales UK.
Anup K SharmaDepartment of Breast Surgery, St. George's Hospital and Medical School, University of London, London, UK.
Abdul KasemThe London Breast Institute, Princess Grace Hospital, London, UK.
Kefah MokbelThe London Breast Institute, Princess Grace Hospital, London, UK ; Department of Breast Surgery, St. George's Hospital and Medical School, University of London, London, UK.
The Princess Grace Hospital · GBCardiff University · GBAyub Medical College · PKUniversity of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Death-associated protein 3 (DAP3) is a molecule with a significant role in the control of both apoptosis and anoikis. Apoptosis is the predominant type of programmed cell death (PCD) which may occur in response to irreparable damage to DNA, or in response to induction by inflammatory cells. Anoikis is subset of apoptosis which occurs in epithelial cells in response to detachment from the surrounding matrix. Both apoptosis and anoikis are of interest in the context of carcinogenesis. In this review, we shall discuss apoptosis and anoikis, and the recent literature regarding the role of DAP3 in both these pathways.

Indexed as

AnoikisApoptosisBreast cancerCancerCarcinogenesisDeath-associated protein 3OncogenesisReview

Identifiers

PMID25883535
PMCPMC4399419
OpenAlexW2122401489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.