ReviewDisease markers2015
Prevalence and prognostic implications of vitamin D deficiency in chronic kidney disease.
Review in Disease markers, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Effects of vitamin D or its analogues on the mortality of patients with chronic kidney disease: an updated systematic review and meta-analysis.European journal of clinical nutrition · 2017Pooled it
- Increased risk of vertebral fracture in patients with diabetes: a meta-analysis of cohort studies.International orthopaedics · 2016Pooled it
- Article
- Vitamin D: are all compounds equal?Clinical kidney journal · 2025Article
- Major adverse kidney events among chronic kidney disease patients with vitamin D deficiency.Frontiers in nutrition · 2025Article
- Lower serum magnesium levels are associated with a higher risk of fractures and vascular calcifications in hemodialysis patients.Clinical kidney journal · 2025Article
- Association of Vitamin D Deficiency and Insufficiency with Pathology in Hospitalized Patients.Diagnostics (Basel, Switzerland) · 2023Article
- 24,25-Dihydroxy Vitamin D and Vitamin D Metabolite Ratio as Biomarkers of Vitamin D in Chronic Kidney Disease.Nutrients · 2023Article
- 25-Hydroxyvitamin-D deficiency in chronic kidney disease stages III, IV, and V in South Asian population: a retrospective cohort.SAGE open medicine · 2023Article
- Characteristics and complications of fracture in older adults with chronic kidney disease: a cross-sectional study.Journal of orthopaedic surgery and research · 2022Article
- Air, Land, and Sea: Gene-Environment Interaction in Chronic Disease.The American journal of medicine · 2021Review
- The weak correlation between serum vitamin levels and chronic kidney disease in hospitalized patients: a cross-sectional study.BMC nephrology · 2021Article
- Association between vitamin D levels and mortality in hemodialysis patients: a cohort study.Renal failure · 2020Article
- Vitamin D ameliorates adipose browning in chronic kidney disease cachexia.Scientific reports · 2020Article
- Bone fracture risk factors in prevalent hemodialysis patients.Journal of bone and mineral metabolism · 2020Observational
- Maternal vitamin D deficiency increases the risk of adverse neonatal outcomes in the Chinese population: A prospective cohort study.PloS one · 2018Article
- Vitamin D3 induces vitamin D receptor and HDAC11 binding to relieve the promoter of the tight junction proteins.Oncotarget · 2017Article
- Association of pre-operative estimated GFR on post-operative pulmonary complications in laparoscopic surgeries.Scientific reports · 2017Article
- Review
- Seasonal variations in transition, mortality and kidney transplantation among patients with end-stage renal disease in the USA.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin D is an important nutrient involved in bone mineral metabolism, and vitamin D status is reflected by serum total 25-hydroxyvitamin D (25[OH]D) concentrations. Vitamin D deficiency is highly prevalent in patients with chronic kidney disease (CKD), and nutritional vitamin D supplementation decreases elevated parathyroid hormone concentrations in subgroups of these patients. Furthermore, vitamin D is supposed to have pleiotropic effects on various diseases such as cardiovascular diseases, malignancies, infectious diseases, diabetes, and autoimmune diseases. Indeed, there is cumulative evidence showing the associations of low vitamin D with the development and progression of CKD, cardiovascular complication, and high mortality. Recently, genetic polymorphisms in vitamin D-binding protein have received great attention because they largely affect bioavailable 25(OH)D concentrations. This finding suggests that the serum total 25(OH)D concentrations would not be comparable among different gene polymorphisms and thus may be inappropriate as an index of vitamin D status. This finding may refute the conventional definition of vitamin D status based solely on serum total 25(OH)D concentrations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.