Evidence map›Paper›PMID 25883141›Full record

ArticleNucleic acids research2015

JPred4: a protein secondary structure prediction server.

Alexey Drozdetskiy, Christian Cole, James Procter, Geoffrey J Barton

Abstract read
In one paragraph

Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,017 papers.

0numbers the graph read from it
0cells of the map it votes in
1,017citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,017 citing papers in PubMed.

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  17. Fold-Switching Proteins.Annual review of biophysics · 2026
    Review
  18. Article
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957 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexey DrozdetskiyDivision of Computational Biology, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Christian ColeDivision of Computational Biology, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.ORCID http://orcid.org/0000-0002-2560-2484
James ProcterDivision of Computational Biology, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Geoffrey J BartonDivision of Computational Biology, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK g.j.barton@dundee.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/G022682/1Biotechnology and Biological Sciences Research Council BB/G022686/1Biotechnology and Biological Sciences Research Council BB/J019364/1Biotechnology and Biological Sciences Research Council BB/L020742/1Wellcome Trust 106370/Z/14Wellcome Trust 355-804783Wellcome Trust WT083481Wellcome Trust WT092340
6 · The paper itself

Abstract

JPred4 (http://www.compbio.dundee.ac.uk/jpred4) is the latest version of the popular JPred protein secondary structure prediction server which provides predictions by the JNet algorithm, one of the most accurate methods for secondary structure prediction. In addition to protein secondary structure, JPred also makes predictions of solvent accessibility and coiled-coil regions. The JPred service runs up to 94 000 jobs per month and has carried out over 1.5 million predictions in total for users in 179 countries. The JPred4 web server has been re-implemented in the Bootstrap framework and JavaScript to improve its design, usability and accessibility from mobile devices. JPred4 features higher accuracy, with a blind three-state (α-helix, β-strand and coil) secondary structure prediction accuracy of 82.0% while solvent accessibility prediction accuracy has been raised to 90% for residues <5% accessible. Reporting of results is enhanced both on the website and through the optional email summaries and batch submission results. Predictions are now presented in SVG format with options to view full multiple sequence alignments with and without gaps and insertions. Finally, the help-pages have been updated and tool-tips added as well as step-by-step tutorials.

Indexed as

Protein Structure, SecondarySoftwareAlgorithmsInternetSolventsSolvents

Identifiers

PMID25883141
PMCPMC4489285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.