ArticleNucleic acids research2015
A novel family of integrases associated with prophages and genomic islands integrated within the tRNA-dihydrouridine synthase A (dusA) gene.
Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Discovery of a New Catalogue of Tyrosine-Type Integrases in Bacterial Genomic Islands.Applied and environmental microbiology · 2023Pooled it
- Clarification of the genomic boundaries of prophage Phi2401a in aMicrobiology spectrum · 2026Article
- The tRNA dihydrouridine synthase DusA has a distinct mechanism in optimizing tRNAs for translation.Nucleic acids research · 2026Article
- Genetic Characterization of a Novel Retron Element Isolated from Vibrio mimicus.Microbiology and immunology · 2025Article
- Reclassification of the first Bacillus tropicus phage calls for reclassification of other Bacillus temperate phages previously designated as plasmids.BMC genomics · 2024Article
- Prophage enhances the ability of deep-sea bacteriumMicrobiology spectrum · 2024Article
- Tailless and filamentous prophages are predominant in marine Vibrio.The ISME journal · 2024Article
- Active prophages in coral-associated Halomonas capable of lateral transduction.The ISME journal · 2024Article
- Isolation and identification of a novel phage targeting clinical multidrug-resistantFrontiers in cellular and infection microbiology · 2024Article
- Characterization of the novel temperate Escherichia coli phage phiStx2k.Archives of virology · 2023Article
- Identification and Evolutionary Relationship ofPathogens (Basel, Switzerland) · 2022Article
- Genomic Characterization of a Prophage, Smhb1, That InfectsMicroorganisms · 2021Article
- Archaeal tyrosine recombinases.FEMS microbiology reviews · 2021Review
- Genomic islands targeting dusA in Vibrio species are distantly related to Salmonella Genomic Island 1 and mobilizable by IncC conjugative plasmids.PLoS genetics · 2021Article
- Bacteriophages of Shiga Toxin-ProducingPathogens (Basel, Switzerland) · 2021Review
- Phosphate-Solubilizing BacteriumFrontiers in microbiology · 2021Article
- Acquisition of plasmids conferring carbapenem and aminoglycoside resistance and loss of surface-exposed macromolecule structures as strategies for the adaptation ofMicrobial genomics · 2020Article
- Article
- Essential Gene Clusters Involved in Copper Tolerance Identified inPathogens (Basel, Switzerland) · 2020Article
- Identification of an Integrase That Responsible for Precise Integration and Excision ofFrontiers in microbiology · 2019Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Genomic islands play a key role in prokaryotic genome plasticity. Genomic islands integrate into chromosomal loci such as transfer RNA genes and protein coding genes, whilst retaining various cargo genes that potentially bestow novel functions on the host organism. A gene encoding a putative integrase was identified at a single site within the 5' end of the dusA gene in the genomes of over 200 bacteria. This integrase was discovered to be a component of numerous genomic islands, which appear to share a target site within the dusA gene. dusA encodes the tRNA-dihydrouridine synthase A enzyme, which catalyses the post-transcriptional reduction of uridine to dihydrouridine in tRNA. Genomic islands encoding homologous dusA-associated integrases were found at a much lower frequency within the related dusB and dusC genes, and non-dus genes. Excision of these dusA-associated islands from the chromosome as circularized intermediates was confirmed by polymerase chain reaction. Analysis of the dusA-associated islands indicated that they were highly diverse, with the integrase gene representing the only universal common feature.
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