ArticleThe European respiratory journal2015
Understanding asthma-specific quality of life: moving beyond asthma symptoms and severity.
Article in The European respiratory journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03509311 (Investigation of Physical Activity Level, Cardiorespiratory Fitness and Quality of Life in Patients With Asthma), which is not on this map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of Physical Activity Level, Cardiorespiratory Fitness and Quality of Life in Patients With Asthma
Who cites it
13 citing papers in PubMed, 57 citations in OpenAlex.
- How does the EQ-5D-5L perform in asthma patients compared with an asthma-specific quality of life questionnaire?BMC pulmonary medicine · 2020Trial
- Effect of biologic therapies on quality of life in severe asthma: Findings from the PRISM study.The World Allergy Organization journal · 2024Article
- Economic impact of a more extensive use of FENO testing on the Italian population with asthma.Respiratory research · 2023Article
- Patient experience of moderate asthma attacks: qualitative research in the USA and Germany.Journal of patient-reported outcomes · 2022Article
- Measurement properties of the EQ-5D-Y administered through a smartphone app in children with asthma: a longitudinal questionnaire study.Health and quality of life outcomes · 2022Article
- Health-Related Quality of Life (HRQoL) of Residents with Persistent Lower Respiratory Symptoms or Asthma Following a Sulphur Stockpile Fire Incident.International journal of environmental research and public health · 2022Article
- Patients and doctors group meetings: an innovative way to explore severe asthma backstage.Multidisciplinary respiratory medicine · 2022Article
- Predictors of asthma-related quality of life in a large cohort of asthmatics: A cross-sectional study in a secondary care center.Clinical and translational allergy · 2021Article
- The relationship between asthma control and health-related quality of life in asthma and the role of atopy: a cross-sectional study of Nigerian adult asthmatics.The Pan African medical journal · 2021Observational
- Effectiveness of Benralizumab in Improving the Quality of Life of Severe Eosinophilic Asthmatic Patients: Our Real-Life Experience.Frontiers in pharmacology · 2021Article
- EuroQol (EQ-5D-5L) Validity in Assessing the Quality of Life in Adults With Asthma: Cross-Sectional Study.Journal of medical Internet research · 2019Article
- The construction and validation of the Severe Asthma Questionnaire.The European respiratory journal · 2018Article
- Severe asthma and quality of life.The World Allergy Organization journal · 2017Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
This study identifies the unique contributions of asthma severity, symptoms, control and generic measures of quality of life (QoL) to asthma-specific QoL, as measured by the 12-item RAND Negative Impact of Asthma on Quality of Life scale (RAND-IAQL-12).Using a sample of 2032 adults with asthma, we conducted multiple regression analyses that sequentially examined hypothesised predictors of asthma-specific QoL. The change in variance accounted for and total unique variance accounted for is calculated as hypothesised predictors are added in each step.Our results indicate that asthma severity and asthma symptoms are strong predictors of asthma-specific QoL only when not controlling for aspects of asthma control. In regression models that include other aspects of asthma control, the contributions of both asthma symptoms and severity were substantially reduced, with asthma control and aspects of QoL related to social roles and activities emerging as the strongest predictors of asthma-specific QoL.These findings suggest that researchers measuring the impact of asthma on QoL should also consider the importance of asthma control as measured by the RAND Asthma Control Measure (RAND-ACM) and generic QoL scales that measure aspects of daily life that are uniquely affected by asthma.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.