ArticleNeuroImage2015
cTBS delivered to the left somatosensory cortex changes its functional connectivity during rest.
Article in NeuroImage, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- A systematic review of the neurobiological effects of theta-burst stimulation (TBS) as measured using functional magnetic resonance imaging (fMRI).Brain structure & function · 2023Pooled it
- Altered activation in sensorimotor network after applying rTMS over the primary motor cortex at different frequencies.Brain and behavior · 2020Trial
- The physiological effects of noninvasive brain stimulation fundamentally differ across the human cortex.Science advances · 2020Trial
- Increased Accuracy of Emotion Recognition in Individuals with Autism-Like Traits after Five Days of Magnetic Stimulations.Neural plasticity · 2020Trial
- Brain stimulation reveals crucial role of overcoming self-centeredness in self-control.Science advances · 2016Trial
- Functional specialization of the human posterior parietal cortex in visually and proprioceptively driven reaching corrections.Communications biology · 2025Article
- The alterations of repetitive transcranial magnetic stimulation on the energy landscape of resting-state networks differ across the human cortex.Human brain mapping · 2024Article
- Neuromodulatory transcranial magnetic stimulation (TMS) changes functional connectivity proportional to the electric-field induced by the TMS pulse.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Article
- Effects of continuous versus intermittent theta-burst TMS on fMRI connectivity.Frontiers in human neuroscience · 2024Article
- Subject-specific whole-brain parcellations of nodes and boundaries are modulated differently under 10 Hz rTMS.Scientific reports · 2023Article
- Preliminary evidence of prolonged timing effects of theta-burst stimulation in the reading system.Frontiers in human neuroscience · 2023Article
- The effects of intermittent theta burst stimulation of the unilateral cerebellar hemisphere on swallowing-related brain regions in healthy subjects.Frontiers in human neuroscience · 2023Article
- Neural correlates of beneficial effects of young plasma treatment in aged mice: PET-SPM analyses and neuro-behavioural/molecular biological studies.European journal of nuclear medicine and molecular imaging · 2022Article
- Causal connectivity from right DLPFC to IPL in schizophrenia patients: a pilot study.Schizophrenia (Heidelberg, Germany) · 2022Article
- The neurobiology of misophonia and implications for novel, neuroscience-driven interventions.Frontiers in neuroscience · 2022Review
- Insight Into the Effects of Clinical Repetitive Transcranial Magnetic Stimulation on the Brain From Positron Emission Tomography and Magnetic Resonance Imaging Studies: A Narrative Review.Frontiers in neuroscience · 2022Review
- Predicting Long-Term After-Effects of Theta-Burst Stimulation on Supplementary Motor Network Through One-Session Response.Frontiers in neuroscience · 2020Article
- Frequency-specific noninvasive modulation of memory retrieval and its relationship with hippocampal network connectivity.Hippocampus · 2019Article
- MRI-based visualization of rTMS-induced cortical plasticity in the primary motor cortex.PloS one · 2019Article
- The After-Effects of Theta Burst Stimulation Over the Cortex of the Suprahyoid Muscle on Regional Homogeneity in Healthy Subjects.Frontiers in behavioral neuroscience · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
The primary somatosensory cortex (SI) plays a critical role in somatosensation as well as in action performance and social cognition. Although the SI has been a major target of experimental and clinical research using non-invasive transcranial magnetic stimulation (TMS), to date information on the effect of TMS over the SI on its resting-state functional connectivity is very scant. Here, we explored whether continuous theta burst stimulation (cTBS), a repetitive TMS protocol, administered over the SI can change the functional connectivity of the brain at rest, as measured using resting-state functional magnetic resonance imaging (rs-fMRI). In a randomized order on two different days we administered active TMS or sham TMS over the left SI. TMS was delivered off-line before scanning by means of cTBS. The target area was selected previously and individually for each subject as the part of the SI activated both when the participant executes and observes actions. Three analytical approaches, both theory driven (partial correlations and seed based whole brain regression) and more data driven (Independent Component Analysis), indicated a reduction in functional connectivity between the stimulated part of the SI and several brain regions functionally associated with the SI including the dorsal premotor cortex, the cerebellum, basal ganglia, and anterior cingulate cortex. These findings highlight the impact of cTBS delivered over the SI on its functional connectivity at rest. Our data may have implications for experimental and therapeutic applications of cTBS over the SI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.