ReviewBehavioural brain research2016
Sex differences in behavior and neural development and their role in adolescent vulnerability to substance use.
Review in Behavioural brain research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
57 citing papers in PubMed.
- Substance use patterns from late childhood to mid-adolescence: Updates on the Adolescent Brain Cognitive Development Study.Drug and alcohol dependence reports · 2026Article
- Associations of endocannabinoid serum concentrations with behavioral impulsivity and substance use in late childhood to early adolescence.Drug and alcohol dependence · 2026Article
- Protocol to study neurobiological pathways to adverse patterns of substance use in adolescents with anxiety.Addiction neuroscience · 2026Article
- Premature release of action sequences in adolescent male rats.Frontiers in behavioral neuroscience · 2026Article
- Early nicotine initiation and white matter integrity: Associations from late childhood to mid-adolescence.Drug and alcohol dependence · 2025Article
- Sex-Specific Effects of Early-Life Unpredictability on Hippocampal and Amygdala Responses to Novelty in Adolescents.Biological psychiatry global open science · 2025Article
- Sex Differences in the Striatal Contributions to Longitudinal Fine Motor Development in Autistic Children.Biological psychiatry · 2025Article
- Triple network dynamics and future alcohol consumption in adolescents.Alcohol, clinical & experimental research · 2025Article
- Looking at Philosophy for Children and Its Outcomes Through a Neuroscience Lens.Basic and clinical neuroscience · 2025Review
- Parental Alcohol Use Predicts Neural Emotion Reactivity and Substance Use Intentions in Early Adolescence.The Journal of early adolescence · 2025Article
- A narrative review on alcohol use in women: insight into the telescoping hypothesis from a biopsychosocial perspective.The American journal of drug and alcohol abuse · 2025Review
- Sex differences in reward network activation are linked to problematic substance use among high-risk adolescents.Advances in drug and alcohol research · 2025Article
- Adolescents' neural responses to their parents' emotions: associations with emotion regulation, internalizing symptoms, and substance use.Social cognitive and affective neuroscience · 2024Article
- Prior cocaine use diminishes encoding of latent information by orbitofrontal, but not medial, prefrontal ensembles.Current biology : CB · 2024Article
- Association of Neuromelanin-Sensitive MRI Signal With Lifetime Substance Use in Young Women.The American journal of psychiatry · 2024Article
- Sex-Specific Impacts of Early Life Sleep Disruption: Ethanol Seeking, Social Interaction, and Anxiety Are Differentially Altered in Adolescent Prairie Voles.Developmental psychobiology · 2024Article
- Depressive symptoms, conduct problems and alcohol use from age 13 to 19 in Norway: evidence from the MyLife longitudinal study.Child and adolescent psychiatry and mental health · 2024Article
- Sex differences in distributed error-related neural activation in problem-drinking young adults.Drug and alcohol dependence · 2024Article
- A Cross-Sectional Analysis of Parental Behavior and Adolescent Mental Health in Mexico: Insights into Excessive Alcohol Intake, Tobacco Use, Suicidal Behavior, and Depressive Symptomatology.Healthcare (Basel, Switzerland) · 2024Article
- Morbidity among Adolescent Hypnotic Drug Users in Norway: An Observational Population-Based Study.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Adolescents are especially prone to risky behavior and to the emergence of psychological disorders like substance abuse, anxiety and depression. However, there is a sex (or gender) difference in this vulnerability, with females being more prone to developing internalizing disorders and males being more likely to engage in risky behavior and drug use. While several researchers have proposed that there is a relationship between corticolimbic circuit development and adolescent vulnerability, the current proposed models do not take sex differences into account. In this review, we explore recent findings from both human and rodent studies of sex differences during adolescence. In particular, we consider epidemiological studies on the factors that contribute to the development of substance abuse and internalizing disorders, laboratory studies on reward-related and decision-making behavior, and neuroanatomical studies on the development of several structures in the corticolimbic circuit (i.e., prefrontal cortex [PFC], amygdala and striatum). We then integrate these recent findings into models of adolescent vulnerability to substance use that have previously not addressed sex differences. Lastly, we discuss methodological considerations for the interpretation and design of studies on sex (or gender) differences during adolescence while highlighting some opportunities for future investigations.
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