Evidence map›Paper›PMID 25882628›Full record

ReviewBiochimica et biophysica acta2015

As the fat flies: The dynamic lipid droplets of Drosophila embryos.

Michael A Welte

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Monitoring fatty acid trafficking duringbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Regulation of Metabolic Rhythms by Glial Clocks.Journal of biological rhythms · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Pre-Implantation Bovine Embryo Evaluation-From Optics to Omics and Beyond.Animals : an open access journal from MDPI · 2023
    Review
  14. Wds-Mediated H3K4me3 Modification Regulates Lipid Synthesis and Transport inInternational journal of molecular sciences · 2023
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Michael A WelteDepartment of Biology University of Rochester, RC Box 270211, 317 Hutchison Hall, Rochester, NY 14627, USA. Electronic address: michael.welte@rochester.edu.

Funding

Lipid droplets as protein sequestration sitesR01GM102155 · NIGMS · UNIVERSITY OF ROCHESTER · PI WELTE, MICHAEL ANDREAS · 2013 to 2025
$4.2M
Developmental control of organelle transportR01GM064687 · NIGMS · UNIVERSITY OF ROCHESTER · PI WELTE, MICHAEL ANDREAS · 2002 to 2011
$2.2M
NIGMS NIH HHS GM102155NIGMS NIH HHS GM64687NIGMS NIH HHS R01 GM064687NIGMS NIH HHS R01 GM102155
6 · The paper itself

Abstract

Research into lipid droplets is rapidly expanding, and new cellular and organismal roles for these lipid-storage organelles are continually being discovered. The early Drosophila embryo is particularly well suited for addressing certain questions in lipid-droplet biology and combines technical advantages with unique biological phenomena. This review summarizes key features of this experimental system and the techniques available to study it, in order to make it accessible to researchers outside this field. It then describes the two topics most heavily studied in this system, lipid-droplet motility and protein sequestration on droplets, discusses what is known about the molecular players involved, points to open questions, and compares the results from Drosophila embryo studies to what it is known about lipid droplets in other systems.

Indexed as

AnimalsDrosophila melanogasterDrosophila ProteinsEmbryo, NonmammalianGene Expression Regulation, DevelopmentalLipid DropletsLipid MetabolismMicrotubulesMolecular Motor ProteinsSignal TransductionVideo RecordingDrosophila ProteinsMolecular Motor ProteinsDrosophila embryoLipid dropletMicrotubule motorsProtein sequestration

Identifiers

PMID25882628
PMCPMC4516585

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.