ArticleFertility and sterility2015
Optimal timing for elective egg freezing.
Article in Fertility and sterility, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07225660 (A Randomized Blinded Controlled Trial Assessing Hormonal Optimization), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Blinded Controlled Trial Assessing Hormonal Optimization: Late vs. Immediate Start After Discontinuation of Oral Contraceptives in Assisted Reproductive technologY (HOLIDAY)
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Unlocking the potential of embryos: insight of systematic review and meta-analysis into laser-assisted hatching's role in conquering recurrent implantation failure.Frontiers in reproductive health · 2025Pooled it
- Social Freezing: Pressing Pause on Fertility.International journal of environmental research and public health · 2021Pooled it
- Age-Based Oocyte Yield in Elective Oocyte Cryopreservation: A Retrospective Cohort Study.Diagnostics (Basel, Switzerland) · 2025Article
- Fertility Preservation Knowledge, Perceptions, and Expectations Among Military Health Care Students.Military medicine · 2025Article
- Impact of aging on gene expression in human oocytes: a comparative analysis of young and older patients.Reproductive biology and endocrinology : RB&E · 2025Article
- Balancing choice and socioeconomic realities: analyzing behavioral and economic factors in social oocyte cryopreservation decisions.Frontiers in endocrinology · 2024Article
- Outcomes of Social Egg Freezing: A Cohort Study and a Comprehensive Literature Review.Journal of clinical medicine · 2023Article
- What do female medical students know about planned oocyte cryopreservation and what are their personal attitudes?Journal of assisted reproduction and genetics · 2023Article
- Assisted Reproductive Techniques in Multiple Sclerosis: Recommendations from an Expert Panel.Neurology and therapy · 2023Review
- Clinical efficacy analysis of oocyte cryopreservation: A propensity score matched study.The journal of obstetrics and gynaecology research · 2022Article
- A SART data cost-effectiveness analysis of planned oocyte cryopreservation versus in vitro fertilization with preimplantation genetic testing for aneuploidy considering ideal family size.Fertility and sterility · 2022Article
- Fertility Preservation and Reproductive Potential in Transgender and Gender Fluid Population.Biomedicines · 2022Review
- Oocyte cryopreservation review: outcomes of medical oocyte cryopreservation and planned oocyte cryopreservation.Reproductive biology and endocrinology : RB&E · 2022Review
- Reproduction reimagined.F&S reports · 2021Article
- Oocyte cryopreservation versus ovarian tissue cryopreservation for adult female oncofertility patients: a cost-effectiveness study.Journal of assisted reproduction and genetics · 2021Article
- Article
- Elective oocyte cryopreservation for age-related fertility decline.Journal of assisted reproduction and genetics · 2021Article
- Oocyte Cryopreservation at a Young Age Provides an Effective Strategy for Expanding Fertile Lifespan.Frontiers in reproductive health · 2021Review
- Likelihood of achieving a 50%, 60%, or 70% estimated live birth rate threshold with 1 or 2 cycles of planned oocyte cryopreservation.Journal of assisted reproduction and genetics · 2020Article
- Social freezing of oocytes: a means to take control of your fertility.Upsala journal of medical sciences · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
objectiveTo estimate the optimal age to pursue elective oocyte cryopreservation.
designA decision-tree model was constructed to determine the success and cost-effectiveness of oocyte preservation versus no action when considered at ages 25-40 years, assuming an attempt at procreation 3, 5, or 7 years after initial decision.
settingNot applicable. PATIENT(S): Hypothetical patients 25-40 years old presenting to discuss elective oocyte cryopreservation. INTERVENTION(S): Decision to cryopreserve oocytes from age 25 years to age 40 years versus taking no action. MAIN OUTCOME AND MEASURE(S): Probability of live birth after initial decision whether or not to cryopreserve oocytes. RESULT(S): Oocyte cryopreservation provided the greatest improvement in probability of live birth compared with no action (51.6% vs. 21.9%) when performed at age 37 years. The highest probability of live birth was seen when oocyte cryopreservation was performed at ages <34 years (>74%), although little benefit over no action was seen at ages 25-30 years (2.6%-7.1% increase). Oocyte cryopreservation was most cost-effective at age 37 years, at $28,759 per each additional live birth in the oocyte cryopreservation group. When the probability of marriage was included, oocyte cryopreservation resulted in little improvement in live birth rates. CONCLUSION(S): Oocyte cryopreservation can be of great benefit to specific women and has the highest chance of success when performed at an earlier age. At age 37 years, oocyte cryopreservation has the largest benefit over no action and is most cost-effective.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.