ArticleChinese medical journal2015
Values of the Wells and revised Geneva scores combined with D-dimer in diagnosing elderly pulmonary embolism patients.
Article in Chinese medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Predictive scores for the diagnosis of Pulmonary Embolism in COVID-19: A systematic review.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Pooled it
- Comparison of the Wells score with the revised Geneva score for assessing suspected pulmonary embolism: a systematic review and meta-analysis.Journal of thrombosis and thrombolysis · 2016Pooled it
- Article
- Predictive Value of Wells, Geneva, Bova, and PESI Scores in Elderly Pulmonary Embolism Patients.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Influence of an Alternative Diagnosis on the Diagnosis of Pulmonary Thromboembolism.Healthcare (Basel, Switzerland) · 2024Article
- A new biomarker in the diagnosis and prognosis of pulmonary thromboembolism: Serum profilin-1.Heliyon · 2024Article
- Review
- Comparison of VTE risk scores in guidelines for VTE diagnosis in nonsurgical hospitalized patients with suspected VTE.Thrombosis journal · 2023Article
- Revision of Clinical Pre-Test Probability Scores in Hospitalized Patients with Pulmonary Embolism and SARS-CoV-2 Infection.Reviews in cardiovascular medicine · 2023Article
- DIAGNOSIS OF PULMONARY EMBOLISM IN THE EMERGENCY DEPARTMENT.Acta clinica Croatica · 2022Article
- Effectiveness of Clinical Decision Tools in Predicting Pulmonary Embolism.Pulmonary medicine · 2021Article
- Age-dependent diagnostic accuracy of clinical scoring systems and D-dimer levels in the diagnosis of pulmonary embolism with computed tomography pulmonary angiography (CTPA).European radiology · 2019Article
- Negative D-dimer testing excludes pulmonary embolism in non-high risk patients in the emergency department.Emergency radiology · 2017Article
- Current Clinical Management Status of Pulmonary Embolism in China.Chinese medical journal · 2017Article
- Diagnostic management of inpatients with a positive D-dimer test: developing a new clinical decision-making rule for pulmonary embolism.Pulmonary circulationArticle
- Cardiac troponin trends and severity in chronic obstructive pulmonary disease exacerbation: Are limits properly associated for Intensive Care Unit outcome?Lung India : official organ of Indian Chest SocietyArticle
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPulmonary embolism (PE) can be difficult to diagnose in elderly patients because of the coexistent diseases and the combination of drugs that they have taken. We aimed to compare the clinical diagnostic values of the Wells score, the revised Geneva score and each of them combined with D-dimer for suspected PE in elderly patients.
methodsThree hundred and thirty-six patients who were admitted for suspected PE were enrolled retrospectively and divided into two groups based on age (≥65 or <65 years old). The Wells and revised Geneva scores were applied to evaluate the clinical probability of PE, and the positive predictive values of both scores were calculated using computed tomography pulmonary arteriography as a gold standard; overall accuracy was evaluated by the area under the curve (AUC) of receiver operator characteristic curve; the negative predictive values of D-dimer, the Wells score combined with D-dimer, and the revised Geneva score combined with D-dimer were calculated.
resultsNinety-six cases (28.6%) were definitely diagnosed as PE among 336 cases, among them 56 cases (58.3%) were ≥65 years old. The positive predictive values of Wells and revised Geneva scores were 65.8% and 32.4%, respectively (P < 0.05) in the elderly patients; the AUC for the Wells score and the revised Geneva score in elderly was 0.682 (95% confidence interval [CI]: 0.612-0.746) and 0.655 (95% CI: 0.584-0.722), respectively (P = 0.389). The negative predictive values of D-dimer, the Wells score combined with D-dimer, and the revised Geneva score combined with D-dimer were 93.7%, 100%, and 100% in the elderly, respectively.
conclusionsThe diagnostic value of the Wells score was higher than the revised Geneva score for the elderly cases with suspected PE. The combination of either the Wells score or the revised Geneva score with a normal D-dimer concentration is a safe strategy to rule out PE.
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