Evidence map›Paper›PMID 25881246›Full record

SynthesisBMC musculoskeletal disorders2015

Anterior cervical discectomy and fusion may be more effective than anterior cervical corpectomy and fusion for the treatment of cervical spondylotic myelopathy.

Li Guan, Yong Hai, Jin-Cai Yang, Li-Jin Zhou, Xiao-Long Chen

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Li GuanDepartment of Orthopedics, Beijing Chao-Yang Hospital, Capital Medical University, Gong Ti Nan Lu 8#, Chao-Yang District, Beijing, 100020, People's Republic of China. guanli403@163.com.
Yong HaiDepartment of Orthopedics, Beijing Chao-Yang Hospital, Capital Medical University, Gong Ti Nan Lu 8#, Chao-Yang District, Beijing, 100020, People's Republic of China. yonghai_yh@163.com.
Jin-Cai YangDepartment of Orthopedics, Beijing Chao-Yang Hospital, Capital Medical University, Gong Ti Nan Lu 8#, Chao-Yang District, Beijing, 100020, People's Republic of China. yangjincai0206@163.com.
Li-Jin ZhouDepartment of Orthopedics, Beijing Chao-Yang Hospital, Capital Medical University, Gong Ti Nan Lu 8#, Chao-Yang District, Beijing, 100020, People's Republic of China. zhoulj_1010@126.com.
Xiao-Long ChenDepartment of Orthopedics, Beijing Chao-Yang Hospital, Capital Medical University, Gong Ti Nan Lu 8#, Chao-Yang District, Beijing, 100020, People's Republic of China. xiaolongchen_sd@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis meta-analysis explored the efficacy and safety of anterior cervical corpectomy and fusion (ACCF) comparing to anterior cervical discectomy and fusion (ACDF) in treating cervical spondylotic myelopathy (CSM) patients.

methodsSeveral electronic databases were searched combined with manually searching. Thirteen randomized controlled studies were enrolled with 1,062 CSM patients, including 468 patients and 594 patients in the in the ACCF and ACDF group, respectively. The meta-analysis was then performed using the STATA 12.0 software. Crude standard mean difference (SMD) or odds ratio (OR) with their 95% confidence intervals (CI) were calculated.

resultsOur meta-analysis results revealed that CSM patients in ACDF group showed less blood loss than those in ACCF group (SMD = 1.21, 95% CI = 1.03 ~ 1.39, P < 0.001). The operation time of CSM patients in the ACDF group was also obviously shorter than those in ACCF group (SMD = 0.40, 95% CI = 0.23 ~ 0.57, P < 0.001). Furthermore, CSM patients in ACDF group had shorter hospital time than those in ACCF group (SMD = 0.45, 95% CI = 0.21 ~ 0.69, P < 0.001).

conclusionOur findings provide empirical evidence that ACDF may be more effective than ACCF for CSM treatment.

Indexed as

DiskectomySpinal FusionBiomechanical PhenomenaBlood Loss, SurgicalCervical VertebraeHumansIntervertebral DiscLength of StayOdds RatioOperative TimePostoperative ComplicationsRecovery of FunctionRisk FactorsSpinal Cord DiseasesSpondylosisTime Factors

Identifiers

PMID25881246
PMCPMC4344784

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.