Evidence map›Paper›PMID 25881113›Full record

ArticleParasites & vectors2015

Geographical genetic structure of Schistosoma japonicum revealed by analysis of mitochondrial DNA and microsatellite markers.

Mingbo Yin, Hongyan Li, Donald P McManus, David Blair, Jing Su, Zhong Yang, Bin Xu, Zheng Feng, Wei Hu

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Mingbo YinSchool of Life Science, Fudan University, Handan Road 220, Shanghai, 200433, China. yinm@fudan.edu.cn.
Hongyan LiSchool of Life Science, Fudan University, Handan Road 220, Shanghai, 200433, China. wuyan2341199@163.com.
Donald P McManusQIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Qld 4029, Australia. Don.McManus@qimrberghofer.edu.au.
David BlairSchool of Marine and Tropical Biology, James Cook University, Townsville, Qld 4811, Australia. david.blair@jcu.edu.au.
Jing SuSchool of Life Science, Fudan University, Handan Road 220, Shanghai, 200433, China. Su_jing2007@126.com.
Zhong YangSchool of Life Science, Fudan University, Handan Road 220, Shanghai, 200433, China. Zhongyang@fudan.edu.cn.
Bin XuNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, 207 Rui Jin Er Road, Shanghai, 200025, China. xubin677@hotmail.com.
Zheng FengNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, 207 Rui Jin Er Road, Shanghai, 200025, China. zfeng0909@163.com.
Wei HuSchool of Life Science, Fudan University, Handan Road 220, Shanghai, 200433, China. huw@fudan.edu.cn.
Fudan University · CNChinese Center For Disease Control and Prevention · CNCenter for Disease Control · TWJames Cook University · AUNational Institute for Parasitic Diseases · CNQIMR Berghofer Medical Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSchistosoma japonicum is a significant public health risk in parts of China and elsewhere in Southeast Asia. To gain an insight into the epidemiology of schistosomiasis japonica, a detailed investigation of S. japonicum genetic population structure is needed.

methodsUsing three mitochondrial DNA fragments and ten microsatellite loci, we investigated the genetic diversity within and structure among twelve populations of S. japonicum sampled on a geographical scale covering most major endemic areas.

resultsSchistosoma japonicum lineages from Indonesia, the Philippines and Chinese Taiwan were clearly distinct from each other and from those in mainland China. Within mainland China, there was some evidence for genetic divergence between populations from the mountain and lake regions. However, the analysis inferred no clear sub-population structure in the lake region of mainland China. High genetic diversity was found among S. japonicum populations of mainland China and this was significantly higher than those from island regions.

conclusionsHigh genetic diversity within and substantial differentiation among populations were demonstrated in S. japonicum.

Indexed as

Microsatellite RepeatsAnimalsAsia, SoutheasternChinaDNA, MitochondrialGenetic VariationGenotypePhylogenyRNA, HelminthRNA, RibosomalRNA, Ribosomal, 16SSchistosoma japonicumDNA, MitochondrialRNA, HelminthRNA, RibosomalRNA, ribosomal, 12SRNA, Ribosomal, 16S

Identifiers

PMID25881113
PMCPMC4372230
OpenAlexW2100581359

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.