Evidence map›Paper›PMID 25881019›Full record

SynthesisPloS one2015

Standardised mindfulness-based interventions in healthcare: an overview of systematic reviews and meta-analyses of RCTs.

Rinske A Gotink, Paula Chu, Jan J V Busschbach, Herbert Benson, Gregory L Fricchione, M G Myriam Hunink

Retracted 6 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisSystematic ReviewRetracted Publication
In one paragraph

Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. It is linked to 6 registered trials, which are not on this map. Cited by 144 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed, 16 pooled it
86.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03432832 nacompletednot on this mapstarted 2018, after this paper: background citation

Emotion Awareness and Skills Enhancement (EASE) Program: A Clinical Trial

TypeinterventionalSponsorUniversity of PittsburghRan2018 to 2024Enrolled113ConditionsAutism Spectrum DisorderArmsEASE, Supportive Therapy
NCT03720652 nacompletednot on this mapstarted 2019, after this paper: background citation

Mindful Self-Compassion Training to Improve Retention, Job Satisfaction, and Attitudes Toward Dementia Among Long-Term Care Nursing Assistants

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2019 to 2020Enrolled39ConditionsStress and BurnoutArms8-Week Mindful Self-Compassion (MSC), 6-Week Mindful Self-Compassion (MSC)
NCT03771300 nacompletednot on this mapstarted 2018, after this paper: background citation

Efficacy of a Mindfulness-based Intervention Programme With or Without Virtual Reality Support to Reduce Stress in University Students: Protocol for a Randomized Controlled Trial

TypeinterventionalSponsorJavier Garcia CampayoRan2018 to 2019Enrolled280ConditionsMental Health Wellness 1ArmsMindfulness, Mindfulness condition complemented by VR, Relaxation
NCT03904654 nacompletednot on this mapstarted 2019, after this paper: background citation

Mindfulness-based Cognitive Therapy for People With Parkinson's Disease

TypeinterventionalSponsorUniversity of California, San FranciscoRan2019 to 2020Enrolled16ConditionsParkinson Disease, Anxiety, DepressionArmsMindfulness-based cognitive therapy (MBCT)
NCT04159272 nacompletednot on this mapstarted 2019, after this paper: background citation

OPEN.MIND | Can MINDfulness Help Vulnerable Youngsters to Ride a Challenging Emotional Tandem? OPENing up to Positivity While Simultaneously Accepting Negative Feelings

TypeinterventionalSponsorProf. dr. Filip RaesRan2019 to 2022Enrolled450ConditionsEmotional StressArmsMindfulness Training
NCT04469049 nacompletednot on this mapstarted 2020, after this paper: background citation

Mindfulness-based Cognitive Therapy for People With Parkinson's Disease and Caregivers

TypeinterventionalSponsorUniversity of California, San FranciscoRan2020 to 2021Enrolled28ConditionsParkinson Disease, Anxiety, DepressionArmsMindfulness-based cognitive therapy (MBCT)
3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 16 syntheses or guidelines pooled it, 545 citations in OpenAlex.

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  2. The Empirical Status of Mindfulness-Based Interventions: A Systematic Review of 44 Meta-Analyses of Randomized Controlled Trials.Perspectives on psychological science : a journal of the Association for Psychological Science · 2022
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  16. Autism and Mind-Body Therapies: A Systematic Review.Journal of alternative and complementary medicine (New York, N.Y.) · 2017
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84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Rinske A GotinkDepartment of Epidemiology, Erasmus MC, Rotterdam, the Netherlands; Department of Psychiatry, section Medical Psychology and Psychotherapy, Erasmus MC, Rotterdam, the Netherlands; Department of Radiology, Erasmus MC, Rotterdam, the Netherlands.
Paula ChuDepartment of Health Policy, Harvard University, Cambridge, United States of America.
Jan J V BusschbachDepartment of Psychiatry, section Medical Psychology and Psychotherapy, Erasmus MC, Rotterdam, the Netherlands.
Herbert BensonBenson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States of America; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States of America.
Gregory L FricchioneDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, United States of America; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States of America.
M G Myriam HuninkDepartment of Epidemiology, Erasmus MC, Rotterdam, the Netherlands; Department of Radiology, Erasmus MC, Rotterdam, the Netherlands; Department of Health Policy and Management, Harvard School of Public Health, Boston, United States of America.
Harvard University · USErasmus MC · NLErasmus University Rotterdam · NLMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMindfulness-based therapies are being used in a wide range of common chronic conditions in both treatment and prevention despite lack of consensus about their effectiveness in different patient categories.

objectiveTo systematically review the evidence of effectiveness MBSR and MBCT in different patient categories.

methodsA systematic review and meta-analysis of systematic reviews of RCTs, using the standardized MBSR or MBCT programs. We used PRISMA guidelines to assess the quality of the included reviews and performed a random effects meta-analysis with main outcome measure Cohen's d. All types of participants were considered.

resultsThe search produced 187 reviews: 23 were included, covering 115 unique RCTs and 8,683 unique individuals with various conditions. Compared to wait list control and compared to treatment as usual, MBSR and MBCT significantly improved depressive symptoms (d=0.37; 95%CI 0.28 to 0.45, based on 5 reviews, N=2814), anxiety (d=0.49; 95%CI 0.37 to 0.61, based on 4 reviews, N=2525), stress (d=0.51; 95%CI 0.36 to 0.67, based on 2 reviews, N=1570), quality of life (d=0.39; 95%CI 0.08 to 0.70, based on 2 reviews, N=511) and physical functioning (d=0.27; 95%CI 0.12 to 0.42, based on 3 reviews, N=1015). Limitations include heterogeneity within patient categories, risk of publication bias and limited long-term follow-up in several studies.

conclusionThe evidence supports the use of MBSR and MBCT to alleviate symptoms, both mental and physical, in the adjunct treatment of cancer, cardiovascular disease, chronic pain, depression, anxiety disorders and in prevention in healthy adults and children.

Indexed as

MindfulnessAdultChild, PreschoolDelivery of Health CareHumans

Identifiers

PMID25881019
PMCPMC4400080
OpenAlexW1978010209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.