Evidence map›Paper›PMID 25880017›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2015

Ambulatory Blood Pressure Monitoring-Derived Short-Term Blood Pressure Variability in Primary Aldosteronism.

Andrea Grillo, Stella Bernardi, Andrea Rebellato, Bruno Fabris, Moreno Bardelli, Jacopo Burrello, Franco Rabbia, Franco Veglio, Francesco Fallo, Renzo Carretta

Abstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Hypertension and End-Organ Damage in Children--Is the Picture Less Fuzzy Now?Journal of clinical hypertension (Greenwich, Conn.) · 2015
    Article
  6. Aldosterone: Yet Another Path to Blood Pressure Variability and Target Organ Damage.Journal of clinical hypertension (Greenwich, Conn.) · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Andrea GrilloDepartment of Medical, Surgical and Healthy Science, University of Trieste, Trieste, Italy.
Stella BernardiDepartment of Medical, Surgical and Healthy Science, University of Trieste, Trieste, Italy.
Andrea RebellatoDepartment of Medicine-DIMED, University of Padova, Padova, Italy.
Bruno FabrisDepartment of Medical, Surgical and Healthy Science, University of Trieste, Trieste, Italy.
Moreno BardelliDepartment of Medical, Surgical and Healthy Science, University of Trieste, Trieste, Italy.
Jacopo BurrelloDivision of Internal Medicine and Hypertension Unit, Department of Medical Sciences, University of Torino, Torino, Italy.
Franco RabbiaDivision of Internal Medicine and Hypertension Unit, Department of Medical Sciences, University of Torino, Torino, Italy.
Franco VeglioDivision of Internal Medicine and Hypertension Unit, Department of Medical Sciences, University of Torino, Torino, Italy.
Francesco FalloDepartment of Medicine-DIMED, University of Padova, Padova, Italy.
Renzo CarrettaDepartment of Medical, Surgical and Healthy Science, University of Trieste, Trieste, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the short-term blood pressure (BP) variability (BPV) derived from ambulatory blood pressure monitoring (ABPM) in patients with primary aldosteronism (PA), either idiopathic hyperaldosteronism (IHA) or aldosterone-producing adenoma (APA), in comparison with patients with essential hypertension (EH) and normotensive (NT) controls. Thirty patients with PA (16 with IHA and 14 with APA), 30 patients with EH, and 30 NT controls, matched for sex, age, body mass index, and antihypertensive therapy, were studied. The standard deviation (SD) of 24-hour, daytime, and nighttime BP; 24-hour weighted SD of BP; and 24-hour BP average real variability were not different between patients with PA and those with EH (P=not significant). All BPV indices were higher in patients with PA, either IHA or APA subtypes, and patients with EH, compared with NT controls (P<.001 to P<.05). ABPM-derived short-term BPV is increased in patients with PA, and it may represent an additional cardiovascular risk factor in this disease. The role of aldosterone excess in BPV has to be clarified.

Indexed as

AdultAgedBlood PressureBlood Pressure Monitoring, AmbulatoryCase-Control StudiesCross-Sectional StudiesEssential HypertensionFemaleHumansHyperaldosteronismHypertensionMaleMiddle Aged

Identifiers

PMID25880017
PMCPMC8031694

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.