ArticleBMC microbiology2015
Competition between Burkholderia pseudomallei and B. thailandensis.
Article in BMC microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed.
- Genomic characterization of an environmental Burkholderia thailandensis strain from Kerala, India reveals virulence and antimicrobial resistance signatures.BMC genomics · 2025Article
- Carboxyfullerene C60 preserves porcine sperm by enhancing antioxidant capacity and inhibiting apoptosis and harmful bacteria.Journal of animal science · 2024Article
- Machine learning uncovers themSystems · 2023Article
- Disruption of c-di-GMP Signaling Networks Unlocks Cryptic Expression of Secondary Metabolites during Biofilm Growth inApplied and environmental microbiology · 2022Article
- The Burkholderia pseudomalleiMicrobiology spectrum · 2021Article
- Physiological, Morphological and Antioxidant Responses ofFoods (Basel, Switzerland) · 2021Article
- An Overview of Metabolic Activity, Beneficial and Pathogenic Aspects ofMetabolites · 2021Review
- Geographical distribution of Burkholderia pseudomallei in soil in Myanmar.PLoS neglected tropical diseases · 2021Article
- A Search for Anti-Pathogens (Basel, Switzerland) · 2021Article
- Characterization of a Type VI Secretion SystemFrontiers in microbiology · 2021Article
- A study of Rose Bengal against a 2-keto-3-deoxy-d-Journal of enzyme inhibition and medicinal chemistry · 2020Article
- Inhibitors of Bacterial Swarming Behavior.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Review
- Erythritol as a single carbon source improves cultural isolation of Burkholderia pseudomallei from rice paddy soils.PLoS neglected tropical diseases · 2019Article
- Temporal proteomic profiling reveals changes that support Burkholderia biofilms.Pathogens and disease · 2019Article
- An increase in intracellular p62/NBR1 and persistence of Burkholderia mallei and B. pseudomallei in infected mice linked to autophagy deficiency.Immunity, inflammation and disease · 2019Article
- Antibodies in Melioidosis: The Role of the Indirect Hemagglutination Assay in Evaluating Patients and Exposed Populations.The American journal of tropical medicine and hygiene · 2018Article
- Effect of temperature on Burkholderia pseudomallei growth, proteomic changes, motility and resistance to stress environments.Scientific reports · 2018Article
- Presence of B. thailandensis and B. thailandensis expressing B. pseudomallei-like capsular polysaccharide in Thailand, and their associations with serological response to B. pseudomallei.PLoS neglected tropical diseases · 2018Article
- Human Infection with Burkholderia thailandensis, China, 2013.Emerging infectious diseases · 2017Article
- Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundBurkholderia pseudomallei is a Gram-negative bacterium that causes melioidosis, an often fatal disease in tropical countries. Burkholderia thailandensis is a non-virulent but closely related species. Both species are soil saprophytes but are almost never isolated together.
resultsWe identified two mechanisms by which B. pseudomallei affects the growth of B. thailandensis. First, we found that six different isolates of B. pseudomallei inhibited the growth of B. thailandensis on LB agar plates. Second, our results indicated that 55% of isolated strains of B. pseudomallei produced a secreted compound that inhibited the motility but not the viability of B. thailandensis. Analysis showed that the active compound was a pH-sensitive and heat-labile compound, likely a protein, which may affect flagella processing or facilitate their degradation. Analysis of bacterial sequence types (STs) demonstrated an association between this and motility inhibition. The active compound was produced from B. pseudomallei during the stationary growth phase.
conclusionTaken together, our results indicate that B. pseudomallei inhibits both the growth and motility of its close relative B. thailandensis. The latter phenomenon appears to occur via a previously unreported mechanism involving flagellar processing or degradation.
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