ArticleAmerican journal of respiratory and critical care medicine2015
Effect of Direct-to-Consumer Advertising on Asthma Medication Sales and Healthcare Use.
Article in American journal of respiratory and critical care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Characterizing treatment pathways at scale using the OHDSI network.Proceedings of the National Academy of Sciences of the United States of America · 2016Pooled it
- Patient Understanding of Oncology Clinical Trial Endpoints in Direct-to-Consumer Television Advertising.The oncologist · 2023Trial
- The Effect of Including Quantitative Information on Multiple Endpoints in Direct-to-Consumer Prescription Drug Television Advertisements.Medical decision making : an international journal of the Society for Medical Decision Making · 2019Trial
- Visual images of prescription drug benefits in direct-to-consumer television advertisements.Patient education and counseling · 2021Article
- How Internet Contracts Impact Research: Content Analysis of Terms of Service on Consumer Product Websites.JMIR public health and surveillance · 2020Article
- Impact of direct-to-consumer drug advertising during the Super Bowl on drug utilization.Research in social & administrative pharmacy : RSAP · 2020Article
- Overuse and Misuse of Inhaled Corticosteroids Among Veterans with COPD: a Cross-sectional Study Evaluating Targets for De-implementation.Journal of general internal medicine · 2020Article
- Testimonials and Informational Videos on Branded Prescription Drug Websites: Experimental Study to Assess Influence on Consumer Knowledge and Perceptions.Journal of medical Internet research · 2018Article
- Attention to and Distraction from Risk Information in Prescription Drug Advertising: An Eye Tracking Study.Journal of public policy & marketing : JPP&M : an annual publication of the Division of Research, Graduate School of Business Administration, the University of Michigan · 2017Article
- Effect of Direct-to-Consumer Advertising on Statin Use in the United States.Medical care · 2017Article
- Article
- U.S. Food and Drug Administration: Review for the Emergency Physician of Approval Process and Limitations.The western journal of emergency medicine · 2016Review
- Key Features of Academic Detailing: Development of an Expert Consensus Using the Delphi Method.American health & drug benefits · 2016Article
- Article
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Authors and funding
9 authors.
Funding
Abstract
rationaleThe United States is one of only two countries that permit direct-to-consumer advertising (DTCA) of prescription drugs, and many questions remain regarding its effects.
objectivesTo quantify the association between asthma-related DTCA, pharmacy sales, and healthcare use.
methodsThis was an ecological study from 2005 through 2009 using linked data from Nielsen (DTCA television ratings), the IMS Health National Prescription Audit (pharmacy sales), and the MarketScan Commercial Claims data (healthcare use) for 75 designated market areas in the United States. We used multilevel Poisson regression to model the relationship between DTCA and rates of prescriptions and use within and across designated market areas. Main outcome measures include (1) volume of total, new, and refilled prescriptions for advertised products based on pharmacy sales; (2) prescription claims for asthma medications; and asthma-related (3) emergency department use, (4) hospitalizations, and (5) outpatient encounters among the commercially insured. MEASUREMENTS AND MAIN
resultsFour Food and Drug Administration-approved asthma medicines were advertised during the period examined: (1) fluticasone/salmeterol (Advair), (2) mometasone furoate (Asmanex), (3) montelukast (Singulair), and (4) budesonide/formoterol (Symbicort). After adjustment, each additional televised advertisement was associated with 2% (incident rate ratio, 1.02; 95% confidence interval, 1.01-1.03) higher pharmacy sales rate from 2005 through 2009, although this effect varied across the three consistently advertised therapies examined. Among the commercially insured, DTCA was positively and significantly associated with emergency room visits related to asthma (incident rate ratio, 1.02; 95% confidence interval, 1.01-1.04), but there was no relationship with hospitalizations or outpatient encounters.
conclusionsAmong this population, DTCA was associated with higher prescription sales and asthma-related emergency department use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.