Evidence map›Paper›PMID 25879016›Full record

ArticleBioMed research international2015

Chlorhexidine gluconate dressings reduce bacterial colonization rates in epidural and peripheral regional catheters.

Klaus Kerwat, Leopold Eberhart, Martina Kerwat, Dominik Hörth, Hinnerk Wulf, Thorsten Steinfeldt, Thomas Wiesmann

Open access · hybridAbstract readControlled Clinical Trial
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Klaus KerwatDepartment of Anesthesiology and Intensive Care Medicine, University Hospital Marburg, Baldingerstrasse, 35043 Marburg, Germany.
Leopold EberhartDepartment of Anesthesiology and Intensive Care Medicine, University Hospital Marburg, Baldingerstrasse, 35043 Marburg, Germany.
Martina KerwatInstitute of Medical Microbiology and Hygiene, Philipps University Marburg, Hans-Meerwein-Strasse 2, 35043 Marburg, Germany.
Dominik HörthDepartment of Anesthesiology and Intensive Care Medicine, University Hospital Marburg, Baldingerstrasse, 35043 Marburg, Germany ; Department of Trauma, Hand and Reconstructive Surgery, University Hospital Marburg, Baldingerstrasse, 35043 Marburg, Germany.
Hinnerk WulfDepartment of Anesthesiology and Intensive Care Medicine, University Hospital Marburg, Baldingerstrasse, 35043 Marburg, Germany.
Thorsten SteinfeldtDepartment of Anesthesiology and Intensive Care Medicine, University Hospital Marburg, Baldingerstrasse, 35043 Marburg, Germany.ORCID 0000-0002-0135-4826
Thomas WiesmannDepartment of Anesthesiology and Intensive Care Medicine, University Hospital Marburg, Baldingerstrasse, 35043 Marburg, Germany.
Philipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBacterial colonization of catheter tips is common in regional anesthesia and is a suspected risk factor for infectious complications. This is the first study evaluating the effect of CHG-impregnated dressings on bacterial colonization of regional anesthesia catheters in a routine clinical setting.

methodsIn this prospective study, regional anesthesia catheter infection rates were examined in two groups of patients with epidural and peripheral regional catheters. In the first group, regional anesthesia was dressed with a conventional draping. The second group of patients underwent catheter dressing using a CHG-impregnated draping. Removed catheters and the insertion sites were both screened for bacterial colonization.

resultsA total of 337 catheters from 308 patients were analysed. There was no significant reduction of local infections in either epidural or peripheral regional anesthesia catheters in both CHG and conventional groups. In the conventional group, 21% of the catheter tips and 41% of the insertion sites showed positive culture results. In the CHG-group, however, only 3% of the catheter tips and 8% of the insertion sites were colonised.

conclusionCHG dressings significantly reduce bacterial colonization of the tip and the insertion site of epidural and peripheral regional catheters. However, no reductions in rates of local infections were seen.

Indexed as

BandagesAgedAnesthesia, ConductionAnti-Infective Agents, LocalBacterial InfectionsCatheter-Related InfectionsChlorhexidineDelayed-Action PreparationsDermatologic AgentsFemaleHumansMaleTransdermal PatchTreatment OutcomeAnti-Infective Agents, LocalChlorhexidinechlorhexidine gluconateDelayed-Action PreparationsDermatologic Agents

Identifiers

PMID25879016
PMCPMC4386602
OpenAlexW2084880892

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.