Evidence map›Paper›PMID 25879001›Full record

ArticleAdvanced biomedical research2015

Evaluation of relationship between serum levels of anti-müllerian hormone, androgen, and insulin resistant with retrieval oocytes in overweight patients with polycystic ovary syndrome.

Esmat Aghadavod, Nosratollah Zarghami, Laya Farzadi, Mina Zare, Abolfazl Barzegari, Ali Akbar Movassaghpour, Mohammad Nouri

Abstract read
In one paragraph

Article in Advanced biomedical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Esmat AghadavodWomen's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran ; Research Center for Biochemistry and Nutrition In Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran.
Nosratollah ZarghamiDepartment of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Laya FarzadiWomen's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mina ZareDepartment of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran ; Student's Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Abolfazl BarzegariResearch Center for Pharmaceutical Nanotechnology, Research and Development Complex, Tabriz University of Medical Sciences, Tabriz, Iran.
Ali Akbar MovassaghpourHematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad NouriWomen's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran ; Department of Biochemistry and Clinical Laboratories, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to find a correlation between increased body mass index (BMI), insulin resistance (IR), hyperandrogenism, and anti-mullerian hormone (AMH) serum levels with the number of follicles retrieved in polycystic ovary syndrome (PCOS) patients. MATERIALS AND

methodsThe descriptive study was taken on 80 women with average ages of 20-35 years at Alzahra Hospital of Tabriz-Iran who referred for in vitro fertilization. Patients were divided into four groups and serum levels of AMH, testosterone and IR were evaluated at the puncture time.

resultsThe mean number of follicle retrieved was higher in PCOS (P < 0.05) group than non-PCOS patients. There was a negative significant correlation of follicle number with BMI (r = -0.26, P < 0.05). The ratio of follicle numbers in PCOS/overweight group decreased in comparison to PCOS/normal weight group (-30%, P < 0.05) while the follicle numbers in non-PCOS/overweight patients decreased in comparison with non-PCOS/normal weight (-26%, P > 0.05). There was a significant negative association between BMI with AMH (r = -0.59, P < 0.05), BMI with the follicle numbers (r = -0.2, P < 0.05) and a positive association BMI with -IR (r = 0.3, P < 0.05), but there wasn't a significant correlation between BMI with testosterone (r = 0.1, P < 0.5).

conclusionOur finding provides that increasing BMI with direct effect on AMH levels and IR can affect the number of follicles, which are retrieved in these patients.

Indexed as

Anti-mullerian hormonefollicles retrievedinsulin resistancepolycystic ovary syndrometestosterone

Identifiers

PMID25879001
PMCPMC4386207

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